Proliferative Vitreoretinopathy (PVR) describes the process of ectopic cell proliferation that follows rhegmatogenous retinal detachment (RRD). This proliferation commonly occurs in the vitreous or the periretinal area [1]. The retina society first described the term Proliferative Vitreoretinopathy (PVR) in 1983 [2]. The disease was later classified by the Silicone Study Group into different gr...

Proliferative Vitreoretinopathy (PVR) describes the process of ectopic cell proliferation that follows rhegmatogenous retinal detachment (RRD). This proliferation commonly occurs in the vitreous or the periretinal area [1]. The retina society first described the term Proliferative Vitreoretinopathy (PVR) in 1983 [2]. The disease was later classified by the Silicone Study Group into different gr...

Prior studies have shown that intravitreal daunorubicin (9-15 nmol) and triamcinolone acetonide (2 mg) are effective individually in preventing retinal detachment in experimental proliferative vitreoretinopathy. This report compares the efficacy of the combination of daunorubicin (15 nmol) and triamcinolone acetonide (2 mg) with that of daunorubicin alone in a refined experimental model of prol...

To understand the role of tissue inhibitors of metalloproteinase-1 and -2 (TIMP-1 and TIMP-2) in intraocular diseases, levels of TIMP-1 and TIMP-2 were measured by enzyme immunoassay in 47 patients with various ocular diseases: in subretinal fluid of 7 patients with rhegmatogenous retinal detachment and in vitreous of 12 patients with proliferative diabetic retinopathy, 4 with proliferative vit...

Familial exudative vitreoretinopathy (FEVR) is an inherited blinding condition characterized by abnormal development of the retinal vasculature. The authors describe a rare case of the disease associated with severe infantile osteoporosis in a young female patient. The patient was submitted to multiple vitreoretinal procedures in both eyes due to tractional macular detachments. The case was com...