A case of progressive systemic sclerosis is reported. The patient presented with chest pain and an abnormal chest radiograph. Later developments included cardiac involvement with complete heart block. The heart block was successfully managed with an implanted pacemaker.

Progressive systemic sclerosis (PSS) or scleroderma is a multisystem disease which is usually grouped with other systemic rheumatic or connective tissue disorders. As a class these conditions are believed to result, at least in part, from aberrant immunity (Rodnan, 1971). Previous studies have demonstrated that a significant percentage of affected patients develop a spectrum of autoantibodies, ...

A 61-year old woman was referred for analysis of iron-deficiency anemia and intermittent rectal blood loss. At age 35 she had been diagnosed with progressive systemic sclerosis, based on the presence of cutaneous telangiectasias, scleroderma, and pulmonary hypertension. Esophagogastroduodenoscopy revealed no abnormalities; in particular, no gastric antral vascular ectasia was observed. At colon...

Introduction Although there is no universally agreed classification of scleroderma, the following is most generally accepted (Rowell, 1977): (i) morphoea (localized or generalized); (ii) progressive systemic sclerosis; (iii) pseudo scleroderma; (iv) occupational scleroderma. Progressive systemic sclerosis usually begins in middle age, but there is a wide range in the age of onset. Rodnan (1963)...

Systemic sclerosis is a collagen disease with high frequency of oesophageal affection, specially if we use manometry as an evaluation method that has a high rate of clinic complication in high rate of patients. The aim of the study was to evaluate the prevalence of the oesophageal affection through the clinical, radiological, endoscopical and manometrical studies and to compare the results with...

In progressive systemic sclerosis, sometimes referred to as generalized scleroderma, atrophic and sclerotic changes in the skin and internal organs are usually preceded by Raynaud's phenomenon. The disorder, which affects women more frequently than men, forms one of the socalled collagen vascular diseases and, although the aetiology is uncertain, there is evidence to suggest that auto-immune me...

Fatal pancreatic necrosis, secondary to extensive acute arteritic changes, is reported in a case of progressive systemic sclerosis. The patient presented first with hypertension and renal involvement, with active vascular lesions demonstrated by biopsy. The renal lesion at necropsy was inactive, showing the characteristic concentric fibrosis only, while the pancreatic vascular lesions were both...

purpose: to present a case of bilateral enlargement of eyelids in 29 year old man with sclromyxedema syndrome. case report: a 29- year- old man was referred to labbafinegad clinic with bilateral enlargment of upper and lower eyelids, and foreign body sensation since 9 year ago. investigating of patients history show renal deasese(hematuria ) since 9 year ago. in systemic examination the patient...