نتایج جستجو برای: programmed cell death pcd

تعداد نتایج: 1872694  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2004
Cheng-Da Hsu Michelle A Whaley Kristin Frazer Douglas A Miller Kathleen A Mitchell Sheila M Adams Joseph E O'Tousa

We examined the role of programmed cell death (PCD) pathways in retinal degeneration caused by a mutation in the norpA gene. norpA degeneration shows morphological hallmarks of programmed cell death, specifically cytoplasmic condensation and engulfment of the dying photoreceptor cells by neighboring retinal pigment cells. However, genetic mosaic analysis of adult photoreceptors lacking rpr, hid...

Journal: :Genetics 2000
S B Tanenbaum S M Gorski J C Rusconi R L Cagan

Programmed cell death (PCD) in the Drosophila retina requires activity of the irregular chiasmC-roughest (irreC-rst) gene. Loss-of-function mutations in irreC-rst block PCD during retinal development and lead to a rough eye phenotype in the adult. To identify genes that interact with irreC-rst and may be involved in PCD, we conducted a genetic screen for dominant enhancers and suppressors of th...

2017
A. Pedro Gonçalves Jens Heller Asen Daskalov Arnaldo Videira N. Louise Glass

Cell death occurs in all domains of life. While some cells die in an uncontrolled way due to exposure to external cues, other cells die in a regulated manner as part of a genetically encoded developmental program. Like other eukaryotic species, fungi undergo programmed cell death (PCD) in response to various triggers. For example, exposure to external stress conditions can activate PCD pathways...

Journal: :Plant physiology 2014
Humberto H Carvalho Priscila A Silva Giselle C Mendes Otávio J B Brustolini Maiana R Pimenta Bianca C Gouveia Maria Anete S Valente Humberto J O Ramos Juliana R L Soares-Ramos Elizabeth P B Fontes

The binding protein (BiP) has been demonstrated to participate in innate immunity and attenuate endoplasmic reticulum- and osmotic stress-induced cell death. Here, we employed transgenic plants with manipulated levels of BiP to assess whether BiP also controlled developmental and hypersensitive programmed cell death (PCD). Under normal conditions, the BiP-induced transcriptome revealed a robust...

Journal: :The Plant cell 1995
R Mittler E Lam

Programmed cell death (pcd) is activated during the hypersensitive response (HR) of plants to avirulent pathogens. We have recently shown that, similar to pcd in animal cells, nuclei of cells undergoing HR cell death contain fragmented nuclear DNA (nDNA). Here, we report that cell death occurring during the HR is accompanied by an increase in the activity of several deoxyribonucleases. Inductio...

2013
Kyung Min Chung Seong-Woon Yu

Mammalian neural stem cells (NSCs) are of particular interest because of their role in brain development and function. Recent findings suggest the intimate involvement of programmed cell death (PCD) in the turnover of NSCs. However, the underlying mechanisms of PCD are largely unknown. Although apoptosis is the best-defined form of PCD, accumulating evidence has revealed a wide spectrum of PCD ...

2013
Daisuke Igarashi Gerit Bethke Yuan Xu Kenichi Tsuda Jane Glazebrook Fumiaki Katagiri

Programmed cell death (PCD) is a crucial process for plant innate immunity and development. In plant innate immunity, PCD is believed to prevent the spread of pathogens from the infection site. Although proper control of PCD is important for plant fitness, we have limited understanding of the molecular mechanisms regulating plant PCD. Plant innate immunity triggered by recognition of effectors ...

2016
Liselot Dewachter Natalie Verstraeten Maarten Fauvart Jan Michiels

The phenomenon of programmed cell death (PCD), in which cells initiate their own demise, is not restricted to multicellular organisms. Unicellular organisms, both eukaryotes and prokaryotes, also possess pathways that mediate PCD. We recently identified a PCD mechanism in Escherichia coli that is triggered by a mutant isoform of the essential GTPase ObgE (Obg of E. coli). Importantly, the PCD p...

2002
Ron Mittler Eric Lam

Programmed cell death (pcd) is activated during the hypersensitive response (HR) of plants to avirulent pathogens. We have recently shown that, similar to pcd in animal cells, nuclei of cells undergoing HR cell death contain fragmented nuclear DNA (nDNA). Here, we report that cell death occurring during the HR is accompanied by an increase in the activity of several deoxyribonucleases. lnductio...

2005
NORA MOHAMAD ALICIA GUTIÉRREZ MARIEL NÚÑEZ CLAUDIA COCCA GABRIELA MARTÍN GRACIELA CRICCO VANINA MEDINA ELENA RIVERA

Apoptosis or programmed cell death (PCD) is a physiological process characteristic of pluricellular organisms leading to self-destruction of the cell. It is therefore involved in development, homeostasis and host defense. However, a significant difference has been shown between mammalian cell apoptosis and non-mammalian cell apoptosis: mitochondria are implicated only in the former. Execution o...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید