نتایج جستجو برای: prodigiosin

تعداد نتایج: 348  

Journal: :Applied microbiology 1968
D L Lynch T E Worthy G C Kresheck

A procedure was developed for the separation of pigment fractions in a wild-type Serratia marcescens strain. Separation was achieved by column chromatography and elution with several organic solvents. At least six pigment fractions were obtained from the alumina columns by this technique, whereas only four fractions had been reported previously. Spectral and elemental analyses indicate that, in...

Journal: :Applied and Environmental Microbiology 1979

Journal: :Journal of clinical microbiology 1989
D Gargallo-Viola

Enzyme polymorphism and genetic relationship among 99 Serratia marcescens isolates obtained from clinical and environmental sources were determined by analysis of electromorphs in nine enzyme loci encoded by chromosomal genes. Seven of the loci were polymorphic, and 33 distinctive electrophoretic types (ETs) representing multilocus genotypes were identified. Cluster analysis, based on the propo...

Journal: :Microbiology 2004
Sarah J Coulthurst C Léopold Kurz George P C Salmond

The enzyme LuxS is responsible for the production of autoinducer-2 (AI-2), a molecule that has been implicated in quorum sensing in many bacterial species. This study investigated whether there is a luxS-dependent signalling system in the Gram-negative bacteria Serratia spp. Serratia marcescens is a broad-host-range pathogen and an important cause of nosocomial infections. Production of AI-2 ac...

2017
Tristan de Rond Parker Stow Ian Eigl Rebecca E Johnson Leanne Jade G Chan Garima Goyal Edward E K Baidoo Nathan J Hillson Christopher J Petzold Richmond Sarpong Jay D Keasling

Prodiginines, which are tripyrrole alkaloids displaying a wide array of bioactivities, occur as linear and cyclic congeners. Identification of an unclustered biosynthetic gene led to the discovery of the enzyme responsible for catalyzing the regiospecific C-H activation and cyclization of prodigiosin to cycloprodigiosin in Pseudoalteromonas rubra. This enzyme is related to alkylglycerol monooxy...

Journal: :Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2015
Chan-Juan Yu Jiang-Hua Ou Ming-Long Wang Nuerbolati Jialielihan Ya-Hua Liu

PURPOSE Overexpression of survivin in breast cancer cells is associated with aberrant inhibition of apoptosis which leads to massive proliferation of cancer cells. Downregulation of survivin by the anticancer agent prodigiosin can efficiently induce apoptosis in cancer cells. METHODS The levels of survivin expression in breast cancer stem like side population (SP) cells were assessed. Analyze...

Journal: :Frontiers in Bioengineering and Biotechnology 2020

Journal: :OnLine Journal of Biological Sciences 2006

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