Leveraging the differential response of genes to mechanical loading may allow for identification novel therapeutics and we have recently established placental growth factor (PGF) as a mechanically augmented gene which promotes angiogenesis at higher doses osteogenesis lower doses. Herein, sought execute mechanobiology-informed approach regenerative medicine by designing functionalized scaffold ...

This investigation deals with single server queueing system wherein the arrival of the units follow Poisson process with varying arrival rates in different states and the service time of the units is arbitrary (general) distributed. The server may take a vacation of a fixed duration or may continue to be available in the system for next service. Using the probability argument, we construct the ...

Rationale: Paracrine growth factor-mediated crosstalk between cardiac myocytes and nonmyocytes in the heart is critical for programming adaptive cardiac hypertrophy in which myocyte size, capillary density, and the extracellular matrix function coordinately. Objective: To examine the role that placental growth factor (PGF) plays in the heart as a paracrine regulator of cardiac adaptation to str...

Abstract By applying the Takács’ technique about the busy period to the regenerative cycle method, this paper gives the strict proof for the time average distributions of the queue length in M/G/1 without depending on other methods. Moreover we extend its proof from the service time to the completion time(CT). That is, we choose the stochastic behavior on the completion time as the regenerative...

This paper establishes that every random utility discrete choice model (RUM) has a representation that can be characterized by a choice-probability generating function (CPGF) with speci c properties, and that every function with these speci c properties is consistent with a RUM. The choice probabilities from the RUM are obtained from the gradient of the CPGF. Mixtures of RUM are characterized b...

although knowing the time of the occurrence of the earthquakes is vital and helpful, unfortunately it is still unpredictable. by the way there is an urgent need to find a method to foresee this catastrophic event. there are a lot of methods for forecasting the time of earthquake occurrence. another method for predicting that is to know probability density function of time interval between earth...