Capillary permeability estimates from osmotic transient experiments generally have been found to be higher than those obtained from tracer experiments. The question which arises is whether hyperosmolar infusions affect capillary permeability. This was investigated in the rete mirabile of the eel, an organ made up of alternately disposed arterial and venous capillaries. Permeabilities were deter...

The kidney collecting duct is an important renal tubular segment for the regulation of body water and salt homeostasis. Water reabsorption in the collecting duct cells is regulated by arginine vasopressin (AVP) via the vasopressin V2-receptor (V2R). AVP increases the osmotic water permeability of the collecting duct cells through aquaporin-2 (AQP2) and aquaporin-3 (AQP3). AVP induces the apical...

Calcium (Ca) dynamics are incorporated into a mathematical model of the principal cell in the cortical collecting tubule developed earlier in Strieter et al. (1992a. Am. J Physiol. 263:F1063-1075). The Ca components are modeled after the Othmer-Tang model for IP(3)-sensitive calcium channels (1993, in Experimental and Theoretical Advances in Biological Pattern Formation, 295-319). There are IP(...

Chang 8 oil deposit, developed in Hohe and Jihe oil fields at the southern Yi-Shan Slop of Ordos Basin, is regarded as a kind of typical sand reservoir formation with super-low porosity, poor permeability, strong anisotropy as well as locally natural faults and fractures. The previous studies believed that matrix reservoir has a good permeability, whereas fracture reservoir has a reverse manner...

Abstract: This paper presents the results of experimental determination of fiber bed permeability variation with porosity. Flow measurement experiments were designed to measure fiber mat permeability for fiber beds with various fiber volume fractions. Woven fiberglass, chopped fiberglass, and carbon fiber mats were used as reinforcements. The effects of reinforcement type and porosity on fiber ...

Septate junctions (SJs) regulate paracellular permeability across invertebrate epithelia. However, little is known about the function of SJ proteins in aquatic invertebrates. In this study, a role for the transmembrane SJ protein gliotactin (Gli) in the osmoregulatory strategies of larval mosquito (Aedes aegypti) was examined. Differences in gli transcript abundance were observed between the mi...

A rigorous expression is derived that relates exactly the static fluid permeability k for flow through porous media to the electrical formation factor F (inverse of the dimensionless effective conductivity) and an effective length parameter L, i.e., k = L */SF. This length parameter involves a certain average of the eigenvalues of the Stokes operator and reflects information about electrical an...

BACKGROUND Berberine, an isoquinoline derivative alkaloid, has a wide range of pharmacological properties and is considered to have anti-inflammatory and neuroprotective effects. However, there are no reports about the effects and mechanisms of berberine in experimental autoimmune encephalomyelitis (EAE), an established model of multiple sclerosis (MS). METHODOLOGY/PRINCIPAL FINDINGS Female C...