introduction: granular cell tumors (gcts) are rare and mostly benign soft tissue tumors. though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. some malign forms exist, but these have been rarely reported. granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express s-100 and neuro...

Background: The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or to induce apoptosis. However, when mutated, p53 is no longer able to properly accomplish these functions. The aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

      Abstract: development of squamous cell carcinoma from sebaceous cyst is uncommon.in this report , we report a77- old female patient who has had a sebaceous cyst for 20 years. The cyst started to grow during the last year. The patient underwent an operation for excision biopsy and The diagnosis was squamous cell carcinoma.

in females, the most common cancer is breast carcinoma in which squamous cell carcinoma (scc) is a rare type of malignancy. histologically, infiltrating ductal carcinoma is the most common type and lobular, mucinous, and medullary types have lower incidence. pure scc of the breast can originate from the skin, nipple, or epithelium of a deep‑seated dermoid cyst or squamous metaplasia on chronic ...

Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographical locations. In this study, neoplasms from Turkmen Sahra, a region in Golestan province in northeast part of Iran, with a high incidence of squamous cell carcinoma were analyzed for the presence of HPV DNA. Turkmen Sahra is located in the cancer...

background: the aim of this study was to present epidemiological aspects of malignant tumor of head and neck in southeast of iran, with a view toward analyzing the age, gender, site distribution and histological types.  methods: all cases with malignant tumor of the head and neck region from 1999 to 2009 were retrieved from the records of cancer registry center of kerman university of medical s...

introduction: sentinel node mapping has been used for laryngeal carcinoma in several studies, with excellent results thus far.in the current study, we report our preliminary results on sentinel node mapping in laryngeal carcinoma using intra-operative peri-tumoral injection of a radiotracer.   materials and methods: patients with biopsy-proven squamous cell carcinoma of the larynx were included...

to evaluate the effect of adding neoadjuvant chemotherapy to surgery and radiation therapy for locally advanced resectable oral cavity squamous cell carcinoma, 24 patients with t3 or t4a oral cavity squamous cell carcinoma were randomly assigned to surgery alone or docetaxel, cisplatin, and 5-fu (tpf) induction chemotherapy followed by surgery. all patients were planned to receive chemoradiothe...