In this study, we characterized the self-renewal capability, multi-lineage differentiation capacity, and clonogenic efficiency of human dental pulp stem cells (DPSCs). DPSCs were capable of forming ectopic dentin and associated pulp tissue in vivo. Stromal-like cells were reestablished in culture from primary DPSC transplants and re-transplanted into immunocompromised mice to generate a dentin-...

The ultimate goal of a regenerative pulp treatment strategy is to reconstitute normal tissue continuum at the pulp-dentin border, regulating tissue-specific processes of tertiary dentinogenesis. Experimental investigations in mature teeth have shown that a network of extracellular matrix molecules and growth factors signal tertiary dentinogenesis. Application of dentin matrix components or grow...

AIM The aim of this study was to investigate the interaction of a high viscosity glass ionomer cement (GIC) and a composite resin with caries affected dentin and to determine the remineralization levels. MATERIALS AND METHODS In a split mouth design 24 GIC and composite resin atraumatic restorative treatment restorations were made in vivo and the teeth were collected after 2 years and subsequ...

ARTICLE INFO Abstract Article History: Received 2 August 2015 Accepted 2 November 2015 Statement of Problem: There is no enough published data about the shear bond strength of resin modified glass ionomer adhesives on caries-affected primary tooth dentin excavated using minimally invasive systems. Objectives: To evaluate the shear bond strength of 2 different adhesives (one resin modified glass...

Primary cilium is a protruding cellular organelle that has various physiological functions, especially in sensory reception. While an avalanche of reports on primary cilia have been published, the function dental cells remains to be investigated. In this study, we focused dentin-producing odontoblasts. Odontoblasts, like most other cell types, possess cilia, which disappear upon knockdown intra...

This study aimed to compare the push-out bond strength of a bulk-fill and conventional composite resin root dentin primary anterior teeth using 7th-generation bonding agent. in vitro evaluated 24 randomly divided into two groups: Filtek P60 resins. Single Bond Universal adhesive was used for bonding. After filling coronal part canal with resin, were mounted acrylic sliced obtain 1-mm-thick sect...

The purpose of this study was to assess the influence of Er:YAG laser pulse repetition rate on the thermal alterations occurring during laser ablation of sound and demineralized primary dentin. The morphological changes at the lased areas were examined by scanning electronic microscopy (SEM). To this end, 60 fragments of 30 sound primary molars were selected and randomly assigned to two groups ...

Introduction: This study investigated the sealing ability of three different adhesives in primary bovine teeth. Methods: Facial and lingual class V cavities were prepared half in enamel and half in cementum, in 48 bovine primary mandibular incisors and randomly divided into three groups and each group divided to two subgroups. The tested adhesives were XPBond (XP), ClearfilS3 Bond (S3), and Xen...

BACKGROUND Untreated dentin caries in primary teeth is commonly found in preschool children worldwide. Recently, the use of simple non-surgical approaches to manage the situation has been advocated. The aim of the study was to systematically review and evaluate the literature on effectiveness of non-surgical methods in arresting or slowing down the progression of active dentin caries in primary...

The purpose of this study was to evaluate the effect a hemostatic agent containing aluminum chloride on shear bond strength resin-modified glass ionomer cement (RMGIC) dentin primary teeth. Thirty-six extracted non-carious human teeth were collected in study. Dentin surfaces cut and polished. specimens randomly divided into 4 groups; group I: RMGIC without conditioning; II: polyacrylic acid (PA...