نتایج جستجو برای: primary cutaneous t

تعداد نتایج: 1346579  

Journal: :Haematologica 2010
Eva Geissinger Petra Sadler Sabine Roth Tina Grieb Bernhard Puppe Nora Müller Peter Reimer Claudia S Vetter-Kauczok Jörg Wenzel Irina Bonzheim Thomas Rüdiger Hans Konrad Müller-Hermelink Andreas Rosenwald

BACKGROUND CD30(+) T-cell lymphoproliferations comprise a spectrum of clinically heterogeneous entities, including systemic anaplastic large cell lymphomas (ALK(-) and ALK(+)) and primary cutaneous CD30(+) T-cell lymphoproliferative disorders. While all these entities are characterized by proliferation of highly atypical, anaplastic CD30(+) T cells, the expression of T-cell specific antigens in...

Journal: :Blood 2003
Jorge R Toro David J Liewehr Nina Pabby Lynn Sorbara Mark Raffeld Seth M Steinberg Elaine S Jaffe

The importance of alpha beta versus gamma delta T-cell subset antigen expression in the classification of peripheral T-cell lymphomas is still unclear. The objective of this study was to investigate the prognostic value of T-cell receptor-delta 1 (TCR delta 1) expression in primary cutaneous T-cell lymphomas. TCR delta 1 cellular expression was assessed in skin biopsy specimens of 104 individua...

2015
Yusuf Kayar Nuket Bayram Kayar

Primary cutaneous lymphomas are a heterogeneous group of malignancies, exhibiting clinical differences from the systemic lymphomas. Peripheral T-cell lymphomas not uncommonly involve the skin, either as primary or secondary manifestation of the disease. Within this group, three rare provisional entities are delineated in the WHO-EORTC classification for cutaneous lymphomas. We present an extrem...

Journal: :Archives of dermatology 2009
Brian Poligone Lynn D Wilson Antonio Subtil Peter Heald

BACKGROUND Distinct categories of skin lymphoma with preferential site localization and unique clinical behavior, including leg-type primary cutaneous diffuse large B-cell lymphoma, have recently been described. Although these entities are rare, they exhibit reproducible clinicopathologic features, and their recognition may allow more appropriate treatment protocols. OBSERVATIONS We describe ...

Journal: :Blood 2010
Emilio Berti Sebastiano Recalcati Valentina Girgenti Daniele Fanoni Luigia Venegoni Pamela Vezzoli

Extranodal natural killer/T-cell (ENK/T) lymphoma is a rare neoplasm, subcategorized into ENK/T-nasal (ENK/T-N) and ENK/T-nasal type (ENK/T-NT) lymphomas. ENK/T-NT lymphoma with initial presentation in the skin is known as primary cutaneous ENK/T-NT (PC-ENK/T-NT) lymphoma. The aim of this study was to investigate pathogenesis, genomic alterations, and prognosis of cutaneous ENK/T lymphomas to p...

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