BACKGROUND Delayed type hypersensitivity (DTH) response to tuberculin is an important marker of T helper 1 (Th1) mediated acquired immunity against tuberculosis. Depressed DTH responses to tuberculin are observed in immobile elderly individuals with reduced activities of daily living (ADL) scores. Immobility in older people increases the risk of pneumonia related mortality. The decline in the c...

I write in response to the article by Al Jarad et al on this topic. The first study to compare the eYcacy of BCG vaccination and its side eVects using the Bignal multipuncture device with the reusable handle and disposable heads was the pilot study of neonatal BCG vaccination carried out in 1992 for the Department of Health in our health authority. In previous studies in neonates and children u...

I write in response to the article by Al Jarad et al on this topic. The first study to compare the eYcacy of BCG vaccination and its side eVects using the Bignal multipuncture device with the reusable handle and disposable heads was the pilot study of neonatal BCG vaccination carried out in 1992 for the Department of Health in our health authority. In previous studies in neonates and children u...

Soon after Hansen's discovery of M. leprae and Koch's discovery of M. tuberculosis a relationship between the two diseases was considered. In 1924, Sir Leonard Rogers (19) , in a Croonian Lecture on lepros1 researches, stated: "It is now well established that native races in Central Africa, Oceania and America, among whom some of the highest leprosy rates are found, have very low percentages of...

Nine hundred thirty-three persons over 65 years of age, residing in long-term or extended-care facilities in Vancouver, Canada, had tuberculin tests. In addition to PPD-tuberculin, 5 TU and 250 TU, we used PPD-Battey, Candida albicans, mumps, and Trichophyton antigens. Twenty-five percent reacted to 5 TU of tuberculin with reactions of 10 mm or more. There was a progressive, substantial loss of...

I write in response to the article by Al Jarad et al on this topic. The first study to compare the eYcacy of BCG vaccination and its side eVects using the Bignal multipuncture device with the reusable handle and disposable heads was the pilot study of neonatal BCG vaccination carried out in 1992 for the Department of Health in our health authority. In previous studies in neonates and children u...

I write in response to the article by Al Jarad et al on this topic. The first study to compare the eYcacy of BCG vaccination and its side eVects using the Bignal multipuncture device with the reusable handle and disposable heads was the pilot study of neonatal BCG vaccination carried out in 1992 for the Department of Health in our health authority. In previous studies in neonates and children u...

I write in response to the article by Al Jarad et al on this topic. The first study to compare the eYcacy of BCG vaccination and its side eVects using the Bignal multipuncture device with the reusable handle and disposable heads was the pilot study of neonatal BCG vaccination carried out in 1992 for the Department of Health in our health authority. In previous studies in neonates and children u...

  Objective(s): According to the occupationally risk of infection in staff workers who have direct contact with mycobacterium species, we investigated their immunological parameters and compared with healthy purified protein derivative (PPD) negative volunteers.   Materials and Methods : We investigated 20 PPD positive volunteers working at Tuberculin Unit of Razi Vaccine and Serum Research Ins...