conclusions the current study showed that supporting pregnant mother moderates psychological problems such as stress, anxiety, and depression, and hence reduces preterm labor. results the final path model fit well (cfi = 0.96; rmsea = .064). the results showed that depression, anxiety, and stress (β = -0.18) directly, and stressful life events indirectly (β= -0.0396) had the most predict on ges...

The aims of the present study were to compare the levels of mRNA and protein expression of matrix metalloproteinase (MMP)-1, -3, -8 and -9 in human cervical tissue in preterm and term labor as well as not in labor and to determine if corticotropin-releasing hormone (CRH) has an effect on MMP-1, -3 and interleukin (IL)-8 secretion in both preterm and term cervical fibroblasts. Cervical biopsies ...

Preterm birth is defined as birth before the completion of 37 weeks of gestation. The frequency of preterm birth in the United States increased from 10.7% in 1992 to 12.3% in 2003. 1 Preterm births can be categorized as those undertaken because of a specific indication or as spontaneous preterm births. Indicated preterm births occur when a health care provider delivers a baby because of medical...

Background: Women with preterm labor put in an arrest phase by tocolytic therapy, are at increased risk of recurrent preterm labor. The aim of this study is to evaluate vaginal progesterone suppositories as compared to intramuscular type in order to prevent preterm labor in women with episodes of threatened preterm labor. Methods: This prospective longitudinal...

objective background: preterm labor, which defines as live-birth delivery before 37 weeks of gestation is a main determinant of neonatal morbidity and mortality around the world. : the aim of this study was to determine the prevalence of preterm labor in iran by a meta-analysis study, to be as a final measure for policy makers in this field. materials and methods: in this meta-analysis, the dat...

abstract background and objective: nutritional factors are a matter of debate in the etiology of preterm labor. this study was conducted to assess the association of maternal folic acid consumption with preterm labor .comprised and materials and methods: this cohort study was conducted on 191 healthy pregnant women in 2009, referring to two teaching hospitals in tehran (iran). the folic acid in...

Notch signaling plays an important role in regulation of innate immune responses and trophoblast function during pregnancy. To identify the role of Notch signaling in preterm labor, Notch receptors (Notch1-4), its ligands (DLL (Delta-like protein)-1/3/4), Jagged 1/2) and Notch-induced transcription factor Hes1 were assessed during preterm labor. Preterm labor was initiated on gestation day 14.5...

Spontaneous preterm labor is an important complication in perinatology characterized by early onset myometrium contractions leading to labor at preterm. However, the exact mechanism that maintain uterine quiescence and promote increased uterine contractility during labor were incompletely defined. MicroRNAs is a class of short non-coding RNAs that regulate gene expression at the post-transcript...