background: the aim of this perspective study was to assess the frequency of hemoglobinopathy mutational genes among voluntary hemoglobinopathy carrier couples-to-be referred to thalassemia center, shafa hospital, affiliated to ahvaz jondidishapur university of medical sciences (ajuoms), during their first trimester of pregnancy for genetic screening and counseling for prenatal diagnosis (pnd)....

maternity child health is one of the important and essential aspects of health services that must be considered as a priority in administrative programs because mothers and their children more than other people in the community are affected by perilous environmental factors. they are very vulnerable that lead to disease, failure to thrive, inability and death. every year, poor hygiene leads to ...

We realize that the Mage and Donner's observations do not refer specifically to our work on the alterations of the centers that control hearing in SIDS but rather on “the common belief (not only ours but also of other authors) that SIDS is a developmental defect of neurologic origin”. Basically they with this letter to the Editor highlight that there are two lines of thought about the significa...

Prenatal hypoxia-ischemia to the developing brain has been strongly implicated in the subsequent development of the hypertonic motor deficits of cerebral palsy (CP) in premature and full-term infants who present with neonatal encephalopathy. Despite the enormous impact of CP, there is no animal model that reproduces the hypertonia and motor disturbances of this disorder. We report a rabbit mode...

BACKGROUND Cortical gray matter reductions and cerebrospinal fluid (CSF) increases are robust correlates of schizophrenia, but their relationships to obstetric and other etiologic risk factors remain to be established. METHODS Structured diagnostic interviews, obstetric hospital records, and magnetic resonance imaging scans of the brain were obtained for 64 schizophrenic or schizoaffective pa...

BACKGROUND Epidemiological findings suggest an association between low-for-age birth weight and the risk to develop coronary heart diseases in adulthood. During pregnancy, an imbalance between fetal demands and supply may result in permanent alterations of neuroendocrine development in the fetus. We evaluated whether chronic prenatal hypoxia increases arterial sympathetic innervation. METHODS...

Low birth weight (LBW) and hypoxia are among the environmental factors most reliably associated with schizophrenia; however, the nature of this relationship is unclear and both gene-environment interaction and gene-environment covariation models have been proposed as explanations. High-risk (HR) designs that explore whether obstetric complications differentially predict outcomes in offspring at...

Prenatal alcohol exposure (PAE) increases the risk for The Sudden Infant Death Syndrome (SIDS) in human infants. In rat pups, the arousal response to hypoxia is modulated by medullary raphe GABAergic mechanisms. We hypothesized that arousal to hypoxia is impaired by PAE, and is associated with an increase in medullary GABA and enhanced GABAergic activity. Pregnant dams received an ethanol liqui...

background: the need to provide high quality prenatal care services, which take account of women's views and specifi­cally address their need for information, support and communication, has been advocated and group prenatal care, had been sug­gested as one of the ways to achieve this objective. the purpose of this study was to examine the impact of group versus in­dividual prenatal care on sati...