نتایج جستجو برای: preimplantation genetic diagnosis
تعداد نتایج: 1057387 فیلتر نتایج به سال:
Preimplantation genetic diagnosis (PGD) was • fi rst applied in 1988 using a polymerase chain reaction (PCR) protocol to amplify a sequence on the Y chromosome for embryo sexing for patients carrying X-linked disease. Patients have to go through in vitro • fertilization (IVF) so that their embryos may be generated in vitro. Cells are removed from oocytes or embryos and used for the genetic diag...
A retrospective cohort study conducted in 138 patients undergoing their first preimplantation genetic screening (PGS) cycle between January 1, 2006, and December 31, 2007, demonstrated that embryos with good day-3 morphology were more likely to be euploid for X/Y, 8, 15, and 18 than those with poor morphology. The strength of association between euploidy and day-3 morphology was not influenced ...
OBJECTIVES Individuals at risk for Huntington disease face difficult decisions regarding their reproductive options. Most do not wish to pass on the gene for Huntington disease to their children, but may not be prepared themselves to undergo presymptomatic testing and learn their genetic status. For these reasons, many at-risk individuals with a family history of HD would choose a method of gen...
The current morphologically based selection of human embryos for transfer cannot detect chromosome aneuploidies. So far, only biopsy techniques have been able to screen for chromosomal aneuploidies in the in vitro fertilization (IVF) embryos. Preimplantation genetic diagnosis (PGD) or screening (PGS) involves the biopsy of oocyte polar bodies or embryonic cells and has become a routine clinical...
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