Objective Infertility affects different aspects of life as well as quality of life (QOL) in infertile couples. Many infertile couples conceive via using Assisted Reproduction Technologies (ART). However, the effect of pregnancy and childbearing on QOL is not known in these couples. This study aim was to evaluate quality of life and general health during pregnancy and after successful treatment ...

OBJECTIVE To review the clinical indications for first trimester ultrasound. OUTCOME Proven clinical benefit from first trimester ultrasound. EVIDENCE MEDLINE search and bibliography reviews in relevant literature. VALUES Content and recommendations reviewed by the principal authors and the Diagnostic Imaging Committee of the Society of Obstetricians and Gynaecologists of Canada. Levels o...

Lesion of toxemia in first trimester pregnan­cies: Lesion of toxemia of pregnancy, compris­ing desidual arteriolar thickening, narrowing, degeneration, and endothelial vacuolization with trophoblastic degeneration and fibrin thrombi attached to degenerated chorionic villi, were evident in 46 (14.1 per cent) of 326 induced first trimester abortioruJ. No clinical features of toxemia were present,...

Objectives: Preeclampsia is best described as a pregnancy-specific syndrome of reduced organ perfusion secondary to vasospasm and endothelial activation. It is severe and clinically important manifestations of placental insufficiency. Our purpose was to study DUSP1 expression in normal human pregnancy and preeclampsia. Study design: We used ELISA, RT-PCR and Immuno-histochemistry to characteriz...

Background: Iron deficiency anemia (IDA) during pregnancy is a common nutritional disorder with adverse effects for the baby, such as premature birth and low birth weight, and the mother, such as cardiovascular symptoms and reduced physical and mental strength. Therefore, identifying factors affective on IDA will assist the improvement of the health of the mother and fetus. This study aimed to ...

KEY CLINICAL MESSAGE Pregnancy outcome after trachelectomy has high risk of complications such as second trimester pregnancy loss and preterm birth. We report beneficial effect of a simple procedure of vaginal occlusion in addition to cerclage in a patient with trachelectomy and two prior second trimester pregnancy losses.

BACKGROUND The objective of this study was to evaluate the clinical outcomes and to discuss the management of women presenting with an invasive cervical cancer during pregnancy. PATIENTS AND METHODS We retrospectively reviewed patients treated for an invasive cervical cancer diagnosed during pregnancy between 1985 and 2000 in our institution. RESULTS Twenty-one pregnant patients among a tot...

BACKGROUND Brain-derived neurotrophic factor (BDNF) is implicated as a causal factor in major depression and is critical to placental development during pregnancy. Longitudinal data on BDNF across the perinatal period are lacking. These data are of interest given the potential implications for maternal mood and fetal growth, particularly among Black women who show ∼2-fold greater risk for deliv...

BACKGROUND We examined the current status of depressive and anxiety symptoms in Japanese women during pregnancy and postpartum. METHODS We asked 220 Japanese women who gave birth to singleton babies at term to answer the two self-administered questionnaires (Whooley's two questions and two-item generalized anxiety disorder scale) at first, second and third trimester of pregnancy and 1 month a...

OBJECTIVE To validate the diagnosis of second trimester miscarriages/deliveries (16+0 weeks to 27+6 weeks of gestation) recorded as miscarriages in the Danish National Patient Registry or spontaneous deliveries in the Danish Medical Birth Registry, and asses the validity of risk factors, pregnancy complications, and cerclage by review of medical records. MATERIALS AND METHODS In a cohort of 2...