An algorithm is presented for the fast and accurate definition of protein structural domains from coordinate data without prior knowledge of the number or type of domains. The algorithm explicitly locates domains that comprise one or two continuous segments of protein chain. Domains that include more than two segments are also located. The algorithm was applied to a nonredundant database of 230...

I argue that taking the Practical Conditionals Thesis (PCT) seriously demands a new understanding of the semantics of such conditionals. Practical Conditionals Thesis: A practical conditional [if A][ought(B)] expresses B’s conditional preferability given A Paul Weirich has argued that the conditional utility of a state of affairs B on A is to be identified as the degree to which it is desired u...

The next generation Web Intelligence (WI) aims at enabling users to go beyond the existing online information search and knowledge queries functionalities and to gain, from the Web,1 practical wisdom for problem solving. To support such a Wisdom Web, we envision that a grid-like computing infrastructure with intelligent service agencies is needed, where these agencies can interact, self-organiz...

This article reviews a systems model of leadership. According to the model, effective leadership is a synthesis of wisdom, creativity, and intelligence (WICS). It is in large part a decision about how to marshal and deploy these resources. One needs creativity to generate ideas, academic (analytical) intelligence to evaluate whether the ideas are good, practical intelligence to implement the id...

The Biblical Book of Job is a wisdom book. Wisdom, in this context, refers to the intellectual discipline taught by the sages of ancient Isreael to provide professionals with a realistic approach to the problems of life. Chapter 30 of the Book of Job is a key-index of ideas that, if followed through the book, discloses a modern scientifically accurate description of a depression that, at times,...

the persian literature, whether verse or prose, is filled with the ethic, moral, mystical, and educational concepts and ideas. among the great poets, sa' di has a specific approach toward these supreme notions. one may notice many moral and educational concepts and attitudes in the 7th & 8th chapters in his golestan. in this research, it has been tried to survey the various factors and gro...