BACKGROUND Surgery for familial adenomatous polyposis (FAP) aims to minimize cancer risk while providing good functional outcome. Colectomy with ileorectal anastomosis and proctocolectomy with ileal pouch-anal anastomosis both offer this, but there is no clear consensus about which is better. METHODS This is a meta-analysis of comparative studies published between 1991 and 2003 reporting earl...

AIMS Restorative proctocolectomy with ileoanal anastomosis is one of the treatments of choice for patients suffering from familial adenomatous polyposis (FAP). However, any residual rectal mucosa left behind after mucosectomy is at risk for the development of neoplasia. CASE REPORT A 31 year old male patient with FAP underwent restorative proctocolectomy with a pelvic ileal pouch-anal anastom...

Abstract Background IL-33/ST2 axis and gut microbiota are important factors in the pathogenesis of IBD with a potential reciprocal influence. controls mucosal healing process during intestinal inflammation. Pouchitis, after restorative proctocolectomy ileal pouch-anal anastomosis, is most common complication. We aimed to explore correlation between cytokines inflammatory pouchitis. Methods 23 p...

The construction of ileal pouch–anal anastomosis (IPAA) is the procedure of choice for patients with ulcerative colitis or familial adenomatous polyposis who require colectomy. Furthermore, IPAA has the advantage of preserving the natural route of defecation, unlike the Brooke’s ileostomy or continent ileostomies. On the other hand, the natural history of patients with the ileal pouch can be co...