The worldwide heparin contamination crisis in 2008 led health authorities to take fundamental steps to better control heparin manufacture, including implementing appropriate analytical and bio-analytical methods to ensure production and release of high quality heparin sodium product. Consequently, there is an increased interest in the identification and structural elucidation of unusually modif...

Congo red staining is rarely the source of false positives for amyloid. On the other hand, the heat artifact due to cautery in surgical specimens adopts some hyaline features, which can mimic amyloid deposits many times. Therefore, we decided to investigate the behavior of these artifacted areas with some of the ancillary techniques that are commonly used when diagnosing amyloidosis: Congo red ...

Decontamination of poultry or animal housing areas over the last few decades has often involved the use of formaldehyde gas which, although very effective [l, 2,3,4], is a known carcinogen [4]. Various approaches have been used to release the gas, which is usually generated by adding formalin to potassium permanganate. The process by which the gas is generated has varied over the years from man...

A simple, sensitive and rapid flow-injection chemiluminescence method has been developed for the determination of ferulic acid based on the chemiluminescence reaction of ferulic acid with potassium permanganate in a nitric acid medium. A strong chemiluminescence signal was observed when ferulic acid was injected into an acidic potassium permanganate solution in a flow-cell. The present method a...

The oxidation of chlorinated ethenes by potassium permanganate (KMnO4) is increasingly being used to remediate contaminated ground water. Typically the remediation of these sites is assessed by tracking changes in the concentrations of the chlorinated compounds and the chloride produced by the reaction. However, this method can be problematic in a fractured bedrock environment, due to the inher...

Objective: The objective of this study is to develop and validate new selective kinetic methods for the determination of Gentamicin in pure and pharmaceutical preparations. Methods: The proposed methods (A and B) are based on the oxidation of Gentamicin drug with alkaline potassium permanganate at fixed temperature. The oxidation reaction was followed spectrophotometrically by measuring the inc...

The present manuscript describes a simple, sensitive, accurate, precise and economical visible spectrophotometric method for the estimation of azithromycin from tablet formulation. The method is based on the reduction of potassium permanganate in alkaline medium with azithromycin. The measurement of decrease in absorbance of potassium permanganate at 547 nm was done, as it decolourises upon red...