نتایج جستجو برای: post transcriptional gene regulation
تعداد نتایج: 1884247 فیلتر نتایج به سال:
MicroRNA (miR) are a class of small non-coding RNA that involved in post-transcriptional gene regulation. Altered expression miR has been associated with several pathological conditions. MicroRNA-124 (miR-124) is an abundantly expressed the brain as well thymus, lymph nodes, bone marrow, and peripheral blood mono-nuclear cells. It plays key role regulation host immune system. Emerging studies s...
Thyroid cancer, which is known as the most common type of endocrine cancer, has seen a growing prevalence in the last few years. On the other hand, only a small percentage of them are associated with malignancy and most of them are benign tumors. Therefore, the first step in the proper management of this type of cancer is to distinguish malignant tumors from benign ones, and today, we are tryin...
The importance of post-transcriptional regulation by small non-coding RNAs has recently been recognized in both pro- and eukaryotes. Small RNAs (sRNAs) regulate gene expression post-transcriptionally by base pairing with the mRNA. Here we use dynamical simulations to characterize this regulation mode in comparison to transcriptional regulation mediated by protein-DNA interaction and to post-tra...
The regulation of the mitochondrial electron transport chain is central to the control of cellular homeostasis. There are significant gaps in our understanding of how the expression of the mitochondrial and nuclear genome-encoded components of the electron transport chain are co-ordinated, and how the assembly of the protein complexes that constitute the electron transport chain are regulated. ...
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