BACKGROUND High-risk human papillomavirus (hrHPV) testing has higher sensitivity but lower specificity than cytology for cervical (pre)-cancerous lesions. Therefore, triage of hrHPV-positive women is needed in cervical cancer screening. METHODS A cohort of 1,100 hrHPV-positive women, from a population-based screening trial (POBASCAM: n = 44,938; 29-61 years), was used to evaluate 10 triage st...

background: according to age, history and physical examination findings, there are different diagnoses including anatomic lesions for abnormal uterine bleeding (aub). in these conditions, hysteroscopy can be performed as a diagnostic and therapeutic procedure. objective: the aim of this study was defining the diagnostic value of hysteroscopy in evaluating uterine cavity in patients with aub com...

Aim. Little is known about the usefulness of narrow band imaging (NBI) for surveillance of patients after chemoradiotherapy for esophageal neoplasia. Its usefulness in detecting esophageal squamous cell carcinoma (SCC) or high-grade intraepithelial neoplasia (HGIN) in these patients was retrospectively compared to Lugol chromoendoscopy. Patients and Methods. We assessed the diagnostic ability o...

ABBREVIATIONS: ADA: Adenosine Deaminase; AFB: Acid Fast Bacilli; ALP: Alkaline Phosphatase; CPB: Closed Pleural Biopsy; CT: Computerized Tomography; HAI: Hospital Acquired Infection; HIV: Human Immunodeficiency Virus; LDH: Lactate Dehydrogenase; MM: Malignant Mesothelioma; NPV: Negative Predictive Value; PPV: Positive Predictive Value; SGOT: Serum Glutamic Oxaloacetate Transaminase; SGPT: Serum...

Background: Regarding the diagnostic errors of the classic criteria including serum ascites albumin gradient (SAAG), total protein concentration and the adapted Light et al’s criteria in distinguishing transudate versus exudates, we evaluated the ascitic fluid to serum bilirubin ratio as a new criteria in this regard. We also evaluated whether the combination of bilirubin ratio with each of the...

BACKGROUND It has been suggested that high titres of tTG are associated with elevated positive predictive values (PPV) for celiac disease. However, the PPV of a strongly positive tTG will depend on the celiac disease prevalence in the different risk groups of the disease AIMS To assess the PPV of a strongly positive tTG for celiac disease. In addition, to calculate the post-test probability f...

conclusion our results indicate that dsct coronary angiography provides high diagnostic accuracy for the evaluation of cad patients during daily routine practice of a referral cardiovascular setting. background there are numerous studies that address the diagnostic value of dual-source computed tomography (dsct) as an alternative to conventional coronary angiography (cca). however, the benefit ...

BACKGROUND The diagnostic value and the impact of some signs and symptoms in most diseases in primary care have only been studied incompletely. AIM To assess the diagnostic value of macroscopic haematuria for the idagnosis of urological cancer (bladder, kidney) in a general practice setting, as well the influence of age, sex, and some additional signs and symptoms. DESIGN OF STUDY Diagnosti...

Sepsis occurs frequently in the intensive care unit (ICU) and is a leading cause of admission, mortality, and cost. Treatment guidelines recommend early intervention, however positive blood culture results may take up to 48 h. Insulin sensitivity (S(I)) is known to decrease with worsening condition and could thus be used to aid diagnosis. Some glycemic control protocols are able to accurately i...

Objective. To test the value of quantifiable electrical stimuli as a reliable method to assess electroencephalogram reactivity (EEG-R) for the early prognostication of outcome in comatose patients. Methods. EEG was recorded in consecutive adults in coma after cardiopulmonary resuscitation (CPR) or stroke. EEG-R to standard electrical stimuli was tested. Each patient received a 3-month follow-up...