Measurements of ovarian reserve play an important role in predicting the clinical results of assisted reproductive technology (ART). The ideal markers of ovarian reserve for clinical applications should have high specificity in order to determine genuine poor responders. Basal follicle-stimulating hormone levels, antral follicle count, and serum anti-Müllerian hormone (AMH) levels have been sug...

We read with interest the study by Vural et al. [1], who aimed to retrospectively explore the effects of overweight and obesity on IVF outcomes of poor ovarian responders (POR). While the oocyte maturity, total gonadotropin doseduration, and cycle cancellation rates were similar, they observed significantly lower fertilization and clinical pregnancy rates in obese compared to normal and overwei...

BACKGROUND Aim of the study was to investigate whether menstrual cycle length may be considered as a surrogate measure of reproductive health, improving the accuracy of biochemical/sonographical ovarian reserve test in estimating the reproductive chances of women referred to ART. METHODS A retrospective-observational-study in Padua' public tertiary level Centre was conducted. A total of 455 n...

INTRODUCTION Poor response to ovarian stimulation is still a major problem in IVF. The study presents a new stimulation protocol evaluated in a suppopulation of very difficult young poor ovarian responders. MATERIAL AND METHODS The study consists in two sections. The first includes data from a randomized controlled study involving forty-three young patients with a poor ovarian response in at ...

This study was performed to investigate the effect of of transdermal testosterone gel (TTG) on controlled ovarian stimulation (COS) and IVF outcomes and ovarian morphology according to pretreatment duration in poor responders. A total of 120 women were recruited for this pilot study. They were randomized into control, 2 weeks, 3 weeks or 4 weeks TTG treatment groups. For three TTG treatment gro...

BACKGROUND Poor ovarian response to controlled ovarian stimulation is one of the most important interest points in assisted reproduction. Mild ovarian stimulation seems to be preferable to high dose of FSH regimens in women with a history of poor ovarian response in previous protocol. Clomiphene citrate and letrozole alone or in combination with FSH have been used in mild ovarian stimulation pr...