The present study was performed toevaluate the effect of aqueous-methanolic extract of Osbeckia chinensis roots, on the polyol pathway enzymes i.e., aldose reductase (AR) and sorbitol dehydrogenase (SDH) in normoglycemic and diabetic mice of two different age groups (sixand one-month old). Polyol pathway under hyperglycemic condition has been associated with the pathogenesis of diabetic complic...

Eu3+-modified carbon dots (C-dots), 3-5 nm in diameter, were prepared, functionalized, and stabilized via a one-pot polyol synthesis. The role of Eu2+/Eu3+, the influence of O₂ (oxidation) and H₂O (hydrolysis), as well as the impact of the heating procedure (conventional resistance heating and microwave (MW) heating) were explored. With the reducing conditions of the polyol at the elevated temp...

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) was overexpressed and purified from Escherichia coli. Mouse monoclonal antibodies (mAbs) were prepared that react with EBNA1. Eleven high affinity mAbs were recovered. Nine mAbs are isotype IgG (all subisotype IgG(1)) and two mAbs are isotype IgM. All mAbs react strongly with EBNA1 in an ELISA assay while only one mAb (designated 1EB6) fails to...

Aspergillus nidulans wild-type and the extreme carbon catabolite derepressed mutant creAd-30 were characterized with respect to enzyme activities, metabolite concentrations and polyol pools all related to glycolysis, after growth on D-glucose. In the creAd-30 strain the enzymes hexokinase and fructose-6-phosphate reductase showed a two- and threefold increase in activity, respectively, whereas ...

Esterification reactions of some polyols and diols were investigated in the presence of SnO2 and nano-SnO2 and the results were compared with the catalyst-free conditions. High conversions were obtained for most of the reactions in the presence of SnO2 and nano-SnO2 which shows the high catalytic activity of SnO2 and nano-SnO2</sub...

Maria Ahrén, Linnéa Selegård, Fredrik Söderlind, Mathieu Linares, Joanna Kauczor, Patrick Norman, Per-Olov Käll and Kajsa Uvdal, A simple polyol-free synthesis route to Gd2O3 nanoparticles for MRI applications: an experimental and theoretical study, 2012, Journal of nanoparticle research, (14), 8. http://dx.doi.org/10.1007/s11051-012-1006-2 Copyright: Springer Verlag (Germany) http://www.spring...

Two highly convergent syntheses of a fully protected C1-C19 polyol subunit of the brasilinolide family of immunosuppressive macrolides are described, exploiting boron-mediated 1,5-anti aldol couplings to form the C8-C9 and C13-C14 bonds.

UNLABELLED BACKGROUND Lignin is one of the three major components in plant cell walls, and it can be isolated (dissolved) from the cell wall in pretreatment or chemical pulping. However, there is a lack of high-value applications for lignin, and the commonest proposal for lignin is power and steam generation through combustion. Organosolv ethanol process is one of the effective pretreatment ...

With diabetes reaching epidemic proportions, there is an urgent need for reliable treatment strategies for microvascular (retinopathy, neuropathy, and nephropathy) and macrovascular (coronary heart disease and stroke) diabetes complications. The role of diabetic hyperglycemia in the development of complications has been extensively studied and a number of biochemical pathways activated by hyper...