In this article, the biodegradable polylactide/hyaluronic acid (PLA/HA) composites were prepared by a melt blending method. In addition, the acrylic acid grafted polylactide (PLA-g-AA) was studied as an alternative to PLA. The samples were characterized by a fourier transform infrared (FTIR) spectroscopy, a nuclear magnetic resonance (NMR), a differential scanning calorimetry (DSC), an Instron ...

Abstract Although microplastics are ubiquitous in today’s natural environments, our understanding of the materials, quantities, and particle sizes involved remains limited. The recovery from different types environmental matrices requires standardized matrix digestion protocols that allow inter-laboratory comparisons have no effect on polymers themselves. A number commonly used methods rely oxi...

docetaxel (dtx) is one of the most widely used drugs in oncology due to its high efficacy against several cancers. though, its routine clinical administration, formulated in tween 80, causes serious side effects. polylactide-co-glycolide (plga), biodegradable polyester synthesized and approved for human use, is employed to overcome this problem. in this investigation, we compare the cytotoxic m...

Stereocomplexation between enantiomeric poly(l-lactide) (PLLA) and poly(d-lactide) (PDLA) provides an avenue to greatly enhance performance of eco-friendly polylactide (PLA). Unfortunately, although the manufacturing of semicrystalline polymers generally involves melt processing, it is still hugely challenging to create high-performance stereocomplexed polylactide (sc-PLA) products from melt-pr...

Nanotechnology is a promising approach both for restoring or enhancing activity of old and conventional antimicrobial agents and for treating intracellular infections by providing intracellular targeting and sustained release of drug inside infected cells. The present paper introduces a formulation study of gentamicin loaded biodegradable nanoparticles (Nps). Solid-oil-in water technique was st...

To improve the interfacial bonding of sisal fiber-reinforced polylactide biocomposites, polylactide (PLA) and sisal fibers (SF) were melt-blended to fabricate bio-based composites via in situ reactive interfacial compatibilization with addition of a commercial grade epoxy-functionalized oligomer Joncryl ADR@-4368 (ADR). The FTIR (Fourier Transform infrared spectroscopy) analysis and SEM (scanni...

The instability of PEGylated polylactide micelles is a challenge for drug delivery. Stereocomplex interaction between racemic polylactide chains with different configurations provides an effective strategy to enhance the stability of micelles as the nanocarriers of drugs. In this work, a stereocomplex micelle (SCM) self-assembled from the amphiphilic triblock copolymers comprising poly(ethylene...

This review focuses on the polyesters such as polylactide and polyhydroxyalkonoates, as well as polyamides produced from renewable resources, which are currently among the most promising (bio)degradable polymers. Synthetic pathways, favourable properties and utilisation (most important applications) of these attractive polymer families are outlined. Environmental impact and in particular (bio)d...

Polylactide (PLA) is the leading bioderived polymer produced commercially by the metal-catalyzed ring-opening polymerization of lactide. Control over tacticity to produce stereoblock PLA, from rac-lactide improves thermal properties but is an outstanding challenge. Here, phosphasalen indium catalysts feature high rates (30±3 m-1  min-1 , THF, 298 K), high control, low loadings (0.2 mol %), and ...