Women with polycystic ovary syndrome who present with hyperandrogenemia, hyperinsulinemia, and insulin resistance appear to be at high risk of cardiovascular disease. Elevated levels of endothelin-1, a marker of vasculopathy, have been reported in insulin-resistant subjects with endothelial dysfunction. Male gender also seems to be an aggravating factor for cardiovascular disease. In this study...

Background: Polycystic ovary syndrome is a common endocrine disorder with 3-7% prevalence in the general population and 10% in women of childbearing. This rate has increased in infertile women. The main composition of this syndrome includes anovulation or olygoovulation, clinical and laboratory signs of increased androgens and observation polycystic ovaries on ultrasound in evaluation. In this ...

Polycystic ovary syndrome is the most common endocrinopathy among reproductive-aged women in the United States, affecting approximately 7% of female patients. Although the pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. Metabolic syndrome is twice as common in patients with pol...

BACKGROUND Polycystic ovaries (PCO) are described on ultrasound scan as the “presence of 12 or more follicles in each ovary measuring 2–9 mm in diameter, and/or increased ovarian volume (>10 ml)”1. Polycystic ovarian syndrome (PCOS) or disease (PCOD) is diagnosed when polycystic ovaries are associated with chronic anovulation and clinical and/or biochemical androgen excess (typically featured a...

this study was designed to investigate the effect of environmental factors on the appearance of polycystic ovaries (pco) during the first two decades of life. ninety-four female-female twins who underwent a transabdominal ultrasound at the royal hospital for women were sent a questionnaire asking about their birth details, feeding history as a baby, childhood illnesses and vaccination as well a...

background: polycystic ovary syndrome (pcos) is the most common endocrine disorder in reproductive women. nearly 10% of young women in this period involved. although factors such as insulin resistance, hyper insulinemia, obesity and dietary are suggested to be associated with pcos, cause of pcos is not completely understood. dairy products (a key component of the usual diet) of participants can...

objective: polycystic ovary syndrome (pcos) is one of the most common endocrine disorders in women. metformin is a biguanide commonly used to improve pcos symptoms. effect of metformin on the levels of serum homocysteine (hcy) in pcos women is unclear. the aim of this study is evaluating the effect of metformin administration on serum hcy levels and metabolic parameters of pcos patients. materi...

in order to evaluate the effects of short course administration of dexamethasone (dex) combined with clomiphene citrate (cc) in cc-resistant patients with polycystic ovary syndrome (pcas) and normal dheas, a prospective, double blind, placebo controlled, randomized study was undertaken at referral university hospitals, two-hundred and thirty women with pcos and normal dheas who failed to ovulat...