With the purpose of gaining insights into the mechanisms of ion uptake and permeation in desalination membranes, MD investigation of a model polyamide membrane was carried out. A relatively large membrane (45K atoms) was assembled, which closely matched real desalination membrane in terms of chemistry and water permeability. Simulations demonstrate that the mechanism of ion uptake distinctly di...

The advancement of DNA-based bionanotechnology requires efficient strategies to functionalize DNA nanostructures in a specific manner with other biomolecules, most importantly peptides and proteins. Common DNA-functionalization methods rely on laborious and covalent conjugation between DNA and proteins or peptides. Pyrrole-imidazole (Py-Im) polyamides, based on natural minor groove DNA-binding ...

In this research, modification on the ultrafiltration (UF) membrane by synthesis of a thin layer of polyamide selective layer was designed for high performances of forward osmosis (FO) water treatment. Two monomers, m-Phenylenediamine (MPD) and Trimesoyl chloride (TMC) with different concentrations of MPD (2.0% w/v and 1.0% w/v) were reacted with TMC (0.15% w/v) for interfacial polymerization (...

In this paper, we present a novel and low - cost method for preparing copper sulfide films on polyamide. Non-treated as well pre-treated PA6 by 3 different methods (in boiled water; in NaOH solution; water then solution) were used the formation of Cu2S layers sorption-diffusion method. Molten sulfur has been sulfurization agent. The XRD, FTIR, UV-VIS to characterize structural, optical, electri...

In order to determine whether there is an orientation preference of pyrrole-imidazole (Py-Im) polyamide dimers with respect to the 5′-3′ direction of the backbone in the DNA helix, equilibrium association constants (Ka) were determined for a series of six-ring hairpin polyamides which differ with respect to substitution at the N and C termini. Affinity cleaving experiments using hairpin polyami...

Remarkable changes of properties result from systematically varying the surface functionality of polyamide dendrimers within a single generation.

In this work, polyamide (PA)/silica nanocomposite films prepared by dissolution method of composite mixing were investigated. The morphology of nanocomposite films were characterized using scanning electron microscope (SEM), reveals that nano silica powder were uniformly dispersed on PA silica nanocomposite film. Chemical composition of film was confirmed by Fourier transform infrared spectrosc...

several novel composite membranes were prepared to separate and recycle amoxicillin from pharmaceutical wastewater via nanofiltration process. the synthesis of these membranes included three stages: 1- preparation of polysulfone ultrafiltration membranes as a support via phase separation process, 2- modification of its surface by interfacial polymerization as a selective layer (polyamide), and ...

Disclosed is an inhibitor of the expression of CTGF gene, which comprises a pyrrole-imidazole polyamide. The pyrrole-imidazole polyamide has an N-methylpyrrole unit (hereinafter, referred to as “Py”), an N-methylimidazole unit (hereinafter, referred to as “Im”) and a ϝ-aminobutanoic acid unit. In the pyrrole-imidazole polyamide, the region of the ϝ-aminobutanoic acid unit is folded to form an U...