Molecular carbon imides featuring 12-fold [5]helicenes around four cores are reported by Guogang Liu, Yan Li, Zhaohui Wang et al. in their Research Article (e20224769). A molecule is shown the middle, surrounded building blocks of perylene diimides and benzenes.

in this research, modification on the ultrafiltration (uf) membrane by synthesis of a thin layer of polyamide selective layer was designed for high performances of forward osmosis (fo) water treatment. two monomers, m-phenylenediamine (mpd) and trimesoyl chloride (tmc) with different concentrations of mpd (2.0% w/v and 1.0% w/v) were reacted with tmc (0.15% w/v) for interfacial polymerization (...

The mechanochemical N-alkylation of imide derivatives was studied. Reactions under solvent-free conditions in a ball mill gave good yields and could be put in place of the classical solution conditions. The method is general and can be applied to various imides and alkyl halides. Phthalimides prepared under ball milling conditions were used in a mechanochemical Gabriel synthesis of amines by th...

A metal-free radical oxidative carbonylation of alkanes is demonstrated, yielding esters and imides by means of di-tert-butylperoxide as an oxidant. Various alkanes, alcohols and amides were compatible in this system generating the desired carbonyl products in up to 86% yields. We proposed a plausible radical cross-coupling process based on the preliminary mechanistic studies.

Nitrogen heterocycles are ubiquitous in natural products and pharmaceuticals. Herein, we disclose a nitrogen complexation strategy that employs a strong Brønsted acid (HBF4) or an azaphilic Lewis acid (BF3) to enable remote, non-directed C(sp(3))-H oxidations of tertiary, secondary, and primary amine- and pyridine-containing molecules with tunable iron catalysts. Imides resist oxidation and pro...

BACKGROUND Repetitive endothelial damage from dialysis membrane incompatibility is a probable cause of accelerated atherosclerosis in haemodialysis patients. Consequently pulse wave velocity (PWV), a measure of arterial stiffness, was utilized as a surrogate marker of vascular dysfunction during dialysis with two commonly used synthetic dialysers. METHODS PWV was monitored before, during and ...

The zinc finger protein EVI1 is causally associated with acute myeloid leukemogenesis, and inhibition of its function with a small molecule therapeutic may provide effective therapy for EVI1-expressing leukemias. In this paper we describe the development of a pyrrole-imidazole polyamide to specifically block EVI1 binding to DNA. We first identify essential domains for leukemogenesis through str...

ABSTRACT A Lewis acid–promoted nucleophilic addition of methallyltrimethylsilane to a chiral α-keto imide proceeded with stereoselectivity opposite that predicted from Soai's report. The difference in the structure imides between and our cases might have affected diastereofacial selectivity.