Poliomyelitis has appeared in epidemic form, become endemic on a global scale, and been reduced to near-elimination, all within the span of documented medical history. Epidemics of the disease appeared in the late 19th century in many European countries and North America, following which polio became a global disease with annual epidemics. During the period of its epidemicity, 1900-1950, the ag...

The main challenge of vaccine control of poliomyelitis in the 1980s is in the subtropical and tropical regions of the world where "lameness" surveys in recent years have shown how very high the average annual incidence of paralytic poliomyelitis can be in both rural and urban areas in the absence of epidemics. The procedures by which oral polio vaccine (OPV) rapidly eliminated all or almost all...

A case-control study was carried out between May 1988 and May 1989 to assess the effectiveness of three doses of trivalent oral poliomyelitis vaccine (TOPV3) in children aged 6-35 months in Madras city. All the cases were patients with acute paralytic poliomyelitis who were residing in Madras city and were hospitalized in the Institute of Child Health; they represented 95% of such cases in the ...

OBJECTIVES To ascertain all cases of paralytic poliomyelitis in England and Wales during 1985-91 and to determine the source of infection in each case. DESIGN Descriptive study of cases reported between 1985 and 1991. SETTING All health districts in England and Wales. SUBJECTS Patients normally resident in England and Wales whose clinical features were consistent with paralytic poliomyeli...

The National Poliovirus Reference Laboratory at the Victorian Infectious Diseases Reference Laboratory (VIDRL) is responsible for poliovirus testing for Australia and the Pacific Island countries. It is also a regional reference laboratory for the Western Pacific Region of the World Health Organization. Surveillance for acute flaccid paralysis, a clinical manifestation of poliomyelitis, is coor...

Abstract We aimed to analyze the trend of indicators National Immunization Program (acronym in Portuguese. PNI) children under one-year-old and classify municipalities regarding risk transmission vaccine-preventable diseases (RTVPD) Maranhão from 2010 2021. This ecological time series study was based on secondary data vaccination coverage (VC). homogeneity (VCH). proportion abandonment (PA). RT...

BACKGROUND Global withdrawal of serotype-2 oral poliovirus vaccine (OPV2) took place in April 2016. This marked a milestone in global polio eradication and was a public health intervention of unprecedented scale, affecting 155 countries. Achieving high levels of serotype-2 population immunity before OPV2 withdrawal was critical to avoid subsequent outbreaks of serotype-2 vaccine-derived poliovi...

Post-vaccine adverse reactions are unwanted medical events that concern both the public and healthcare professionals. The objective of this paper is to present a detailed analysis case an extensive local reaction after administration vaccine dose containing diphtheria–tetanus anatoxins. A good knowledge post-vaccine side effects allows for complete correct diagnosis, as well appropriate individ...

This article presents results of the main measures on vaccine coverage carried out in France in children up to six years of age. Vaccine coverage is very high for diphtheria, tetanus, pertussis, and poliomyelitis, and satisfactory for vaccination against Haemophilus influenzae b invasive infections. It will be necessary, however, to increase vaccine coverage against measles, mumps and rubella i...