India is committed to eradication of poliomyelitis by the year 2000. However, India still reported about 58% of all polio cases documented globally in 1995. India has adopted the World Health Organisation’s recommended strategy of National Immunization Days (that is, Pulse Polio Immunization) from the year 1995. Oral polio vaccine (OPV) was introduced at national level in 1985. However, no comm...

POLIOMYELITIS, ASEPTIC MENINGITIS AND ENCEPHALITIS, 1955, 1956 AND 1957. Paralytic Poliomyelitis. The laboratory diagnosis of poliomyelitis has been undertaken in the department since August, 1955. Our aim has been to receive specimens from all notified paralytic cases, and in practice, thanks to the co-operation of the physicians, we have received specimens from over (seems) 95 per cent. of th...

A family group containing four children of whom all showed in varying degree symptoms of poliomyelitis is described. The source of infection and periods of incubation have been followed. Two of the children were proven by inoculation tests to carry the virus of poliomyelitis in the nasopharynx. Of these, one was detected to be a carrier after recovering from a non-paralytic attack of the diseas...

The axonal conduction velocity and the axonal refractory period were determined using electromyographic techniques for 60 single motor units in 11 patients with antecedent poliomyelitis. The results were compared with previous observations in healthy subjects as well as subjects with motor neuron disease. In antecedent poliomyelitis there was a reduced proportion of nerve fibres with low conduc...

D. S. DANE, B.A., M.B. (Cantab.), Lecturer in Microbiology, Queen's University, Belfast with MOYA BRIGGS, B.Sc., and R. T. NELSON, A.I.M.L.T. IN the summer and early autumn of 1957 there was an epidemic of type 1 poliomyelitis in Northern Ireland. The principle area involved was Belfast County Borough (population approximately 450,000), where there were 162 cases of acute poliomyelitis, of whic...

A series of 6 chimpanzees was inoculated orally with stool from a poliomyelitis patient. Three of these animals had been given 170 cc. of homologous, hyperimmune monkey serum prior to inoculation, while three were unprotected. All 6 of the animals were subsequently shown to have poliomyelitis virus in their stools and characteristic lesions in their central nervous systems although none of them...

The infectivity of poliomyelitis virus by the intracutaneous route occurs in certain strains but is not a constant character. The inconsistency of skin infectivity tests indicates that there is some property yet unknown which influences this characteristic. Strains of poliomyelitis virus vary in the degree of immunity produced in experimental monkeys injected with active virus by the intracutan...

1. The Rosenow antistreptococcic poliomyelitis serum concentrated or unconcentrated does not neutralize the virus of poliomyelitis as tested in monkeys. 2. The Pettit antipoliomyelitis horse serum neutralizes the virus only occasionally. 3. "Immune" sheep sera prepared according to the method of Pettit have not neutralized virus even when the normal sera of the same animal have given neutraliza...