Stimuli responsive polymeric (SRP) nanotubes have great potential as nanocarriers of macromolecules due to their large surface areas and release mechanisms that can be activated externally. In this work, we demonstrate vapor phase synthesis of coaxial nanotubes with layers of different SRP polymers for improved release kinetics. Temperature responsive poly(N-isopropylacrylamide) (pNIPAAm), pH r...

This paper studies hydrogels created by photopolymerization with a uniform beam of light. Under some conditions the density profiles of the resulting hydrogels were uniform cylinders, mirroring the illumination profiles. However, under other conditions, gels with hollow cylindrical shapes were formed. We studied the photopolymerization of poly-N-isopropylacrylamide (pNIPAAM), a hydrogel that ha...

We demonstrate a new light-responsive poly(N-isopropylacrylamide) (PNIPAAm) hydrogel nanocomposite incorporating glycidyl methacrylate functionalized graphene oxide (GO–GMA) instead of metallic nanoparticle fillers. GO–GMA is synthesized by esterification with glycidyl methacrylate. GO–GMA incorporated hydrogels are synthesized by photopolymerization of NIPAAm including 4-dimethylaminopyridine ...

The site-specific conjugation of DNA-binding protein (Tus) to self-assembling peptide FEFEFKFKK was demonstrated. Rheology studies and TEM of the corresponding hydrogels (including PNIPAAm-containing systems) showed no significant variation in properties and hydrogel morphology compared to FEFEFKFKK. Critically, we demonstrate that Tus is accessible within the gel network displaying DNA-binding...

poly n-isopropylacrylamide was successfully grafted onto a polystyrene cell culture dish by gamma ray. in this study, the effect of a radiation dose (radiation absorbed dosages of 10, 20, 30, 40 kgy) under appropriate temperature and grafting conditions was investigated. the ftir analysis showed the existence of the graft pnipaam on the substrate. the optimal value of the dose for grafting was ...

INTRODUCTION Chronic low back pain due to intervertebral disc (IVD) degeneration is associated with increased levels of inflammatory mediators. Current medical treatment consists of oral anti-inflammatory drugs to alleviate pain. In this study, the efficacy and safety of a novel thermoreversible poly-N-isopropylacrylamide MgFe-layered double hydroxide (pNIPAAM MgFe-LDH) hydrogel was evaluated f...

Abstract Microfluidic paper-based analytical devices (μPADs) have recently attracted the attention of researchers and industry owing to their various advantages. However, µPADs lack a way control fluid flow; therefore, it is difficult perform complex immunoassays that use multiple reagents replace from area. We developed controllable thermoresponsive valve for μPADs by functionalizing polyvinyl...

Hydrogels have become increasingly popular as immobilization materials for cells, enzymes and proteins for biosensing applications. Enzymatic biosensors that utilize hydrogel as an encapsulant have shown improvements over other immobilization techniques such as cross linking and covalent bonding. However, to date there are no studies which directly compare multiple hydrogel-graphene nanocomposi...