abstract background: sp-a and sp-d are hydrophilic proteins which regulate the inflammatory response of the lung. pasteurella multocida is one of the most common bacteria isolated from calves suffering from shipping fever pneumonia, one of the most problems in dairy herds. objective: evaluation of surfactant content may provide a valuable diagnostic tool for detection of calf pneumonia due to p...

BACKGROUND Pasteurellosis is an uncommon infectious disease in humans mainly caused by Pasteurella multocida infection in neonates and has been rarely reported. OBJECTIVES To review the literature and address the mode of transmission, clinical presentation, laboratory diagnosis, treatment, outcome and potential risk factors related to neonatal pasteurellosis. METHODS A Medline all-languages...

During a pneumonic plague outbreak in Moramanga, Madagascar, we identified 4 confirmed, 1 presumptive, and 9 suspected plague case-patients. Human-to-human transmission among close contacts was high (reproductive number 1.44) and the case fatality rate was 71%. Phylogenetic analysis showed that the Yersinia pestis isolates belonged to group q3, different from the previous outbreak.

BACKGROUND In the summer of 2000, an outbreak of primary pneumonic tularemia occurred on Martha's Vineyard, Massachusetts. The only previously reported outbreak of pneumonic tularemia in the United States also occurred on the island in 1978. METHODS We conducted a case-control study of adults with pneumonic tularemia and investigated the environment to identify risk factors for primary pneumo...

BACKGROUND Pasteurella multocida is a Gram-negative bacterium that causes economically significant infections of a broad range of animal species. Pneumonic and septicaemic pasteurellosis caused by this bacterium remain important problems in pigs, cattle, and water buffaloes in Thailand. The aim of this study was to characterise the virulence-associated gene profiles and to develop an OmpA molec...

Signal peptides of membrane proteins are cleaved by endoplasmic reticulum-resident signal peptidase, and thus, are not present on mature membrane proteins. Here, we report that, contrary to the paradigm, the signal peptide of ruminant CD18, the -subunit of 2-integrins, is not cleaved. Intriguingly, the intact signal peptide of CD18 is responsible for the susceptibility of ruminant leukocytes to...

The primary pneumonic plague outbreaks in Oakland in 1919 and Los Angeles in 1924 constitute good points of reference for epidemiological observations and experimental studies on this form of plague. Retrospective analysis of them reveals some still unanswered questions. In the Oakland outbreak (24), a man went hunting in the hills of Contra Costa County in April 1919 and perhaps took home a sq...

In this study, we used an in vitro coculture system to determine which virulence factor from Pasteurella haemolytica Al was responsible for augmenting bovine polymorphonuclear neutrophil (PMN)-mediated killing of bovine pulmonary artery endothelial cells (BPAEC). A 5"Cr release cytotoxicity assay was used as a measure of BPAEC killing. The mechanisms associated with this BPAEC killing were also...

The article presents the results of studies on use an associated vaccine against salmonellosis and pasteurellosis. It was found that number erythrocytes leukocytes in blood vaccinated animals increases, as well levels hemoglobin, total protein its fraction, which indicate a positive effect hematological parameters content animals.