We thank Yang et al for their comments on our whole body MRI study in patients with polymyalgia rheumatica (PMR). Our previous work in PMR revealed inflammatory changes outside the joint cavity, or ‘extracapsular pattern disease’, in both the shoulder and the hand. 3 In a preliminary analysis of four noncontrast whole-body MRIs in the present cohort, we saw an identical pattern of disease in PM...

BACKGROUND Generic patient-accessible medical records have shown promise in enhancing patient-centred care for patients with chronic diseases. We sought to design, implement and evaluate a patient-accessible medical record specifically for patients undergoing a course of assisted reproduction (IVF or ICSI). METHODS The personal medical record (PMR) database was developed using three formative...

BACKGROUND It is difficult to differentiate polymyalgia rheumatica (PMR) from elderly-onset rheumatoid arthritis (EORA) in clinical practice. We compared FDG-PET/CT findings between patients with PMR and those with EORA and extracted factors useful for differentiating the two disorders. METHODS We compared abnormal FDG accumulation sites and maximum standardized uptake value (SUVmax) between ...

OBJECTIVE To determine the incidence of temporal arteritis (TA) in patients with polymyalgia rheumatica (PMR) using colour Doppler ultrasonography of the temporal arteries. METHODS Ultrasonography was performed in all 127 consecutive patients with newly diagnosed, active PMR seen between 1994 and 2000 and in 127 age- and sex-matched controls. RESULTS Of 102 patients with "pure" PMR, 8% had ...

Only two years separate the initial descriptions of polymyalgia rheumatica (PMR) by Bruce in 1888 and giant cell arteritis (GCA) by Hutchinson in 1890. However, the existence of an association between these two conditions was definitely accepted only in 1964. Even if PMR is generally accepted as a different disease from GCA, some authors deem PMR to be a manifestation of a generalised arteritis...

Mechanisms of the water extracts of Polygoni Multiflori Radix (PMR) and its processed products (PMRP) on liver lipid metabolism were observed in this paper. Aqueous extract of PMR and PMRP was given to nonalcoholic fatty liver model rats, respectively. PMR was better in reducing the contents of very low density lipoprotein (VLDL) than PMRP and the positive control groups. In the aspect of regul...

An artefact may appear in the clinical electroretinogram (ERG) that can interfere with the recording and interpretation of the ERG b wave. This artefact, the photomyoclonic reflex (PMR), was studied by covering the eye containing the recording electrode and stimulating the fellow eye. Records obtained by this technique before and after administration of a modified Van Lint lid block demonstrate...

OBJECTIVE To summarize the evidence about the relationship between polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). METHODS Review of relevant articles from the English-language literature. RESULTS Epidemiologic studies suggest that PMR and GCA are closely related conditions affecting people over 50 years and frequently occurring in the same patient. PMR symptoms have been obser...

OBJECTIVES Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) affect individuals older than 50 years of age and corticosteroids are the mainstay of treatment. The aim of our study was to explore the role of leflunomide as a corticosteroid-sparing agent in GCA and PMR patients. METHODS Patients with difficult-to-treat GCA and PMR were retrospectively identified in the period from 2010...

There has been little basis on which to standardise a diagnosis of polymyalgia rheumatica (PMR), and so 11 rheumatology units in the south and west of Great Britain have collaborated in a study to evaluate possible criteria. Symptoms and laboratory findings claimed to be of diagnostic value in PMR were included in an analysis of the features of 236 patients considered to have unequivocal PMR an...