Product Lifecycle Management (PLM) is one way to improve productivity in all manufacturing companies and this is truer in mechanical Small and Medium Enterprises (SMEs). Nevertheless the implementation of a PLM system is not an easy thing for such companies. SMEs have lots of difficulties to create the right information model in order to improve design efficiency. In this paper we propose a PLM...

OBJECTIVE To establish the occurrence of Periodic Leg Movements (PLM) and Restless Legs Syndrome (RLS) in Spinal Cord Injury (SCI) subjects. METHODS In this study, twenty four patients were submitted to a full night polysomnography and were assessed with Epworth Sleepiness Scale and an adapted form of International Restless Legs Syndrome Scale Rating Scale (IRLS Rating Scale). Control Group (...

The Palmaris longus muscle (PLM) is a slender, fusiform muscle which lies on the flexor surface of the forearm. Its agenesis is considered the most frequent anatomic variation in the muscular system of the human body. The PLM has little functional use to the human upper limb. It is evidenced by former epidemiological studies that the agenesis of the PLM has a strong racial and ethnic variabilit...

Sustainability is a key issue for companies offering products and services on the global market. The ever-increasing worldwide demand for raw materials in combination with the rising costs for materials and energy challenges companies to make their products, processes and services more sustainable. More and more customers are demanding sustainable products and services due to their increased aw...

This paper provides solutions to the real industrial need of adding knowledge layer to commercial PLM systems. PLM systems can be enhanced to be used as Knowledge Management tools to solve the semantic interoperability problem of heterogeneous data. Large amounts of product and machine component data exists in under-utilised databases due to the inability of existing integration approaches to s...

Eighteen patients with restless legs syndrome (RLS) and 4 patients with neuroleptic-induced akathisia (NIA) underwent all-night polysomnographic recordings before and during clonazepam treatment. Ten normal control subjects and 4 non-akathitic psychiatric patients treated with neuroleptics underwent polysomnographic recordings, which were compared with those of the RLS and NIA patients, respect...

This paper proposes a novel methodology of distributed PLM platform deployment. It efficiently incorporates PLM technologies to support collaborative product development in a global enterprise with multiple distributed sites. The methodology systematically analyzes a company’s PLM requirements from the Organizational, Application, and Data perspectives. A customized network configuration plan c...

Phoslactomycins (PLMs), potent and selective inhibitors of serine threonine phosphatases, are of interest for their antitumor and antiviral activity. Multiple analogs and low titers in the fermentation process have hampered the development of this class of natural products. The entire 75-kb PLM biosynthetic gene cluster of Streptomyces sp. HK-803 was cloned, sequenced, and analyzed. The loading...

Product Lifecycle Management (PLM) domain is at a key point in its development: its concepts and technologies are mature. PLM systems not only manage documents but information associated to a product along its lifecycle, such as Bills-Of-Material (BOM) or requirements at different levels of granularity. All the dependencies between concepts lead to complex relationships from which it is not eas...

Recently, the tendency of companies to adopt a PLM (product lifecycle management) strategy is increasing and asks for guidelines and reference frameworks to which screen the own organizational situation and drive improvements. Several scholars and managers have argued about PLM using a business and a technological view. Based on the need of Finmeccanica corporate to provide its companies with a...