BACKGROUND Acetaminophen (APAP)-induced toxicity is a predominant cause of acute hepatic and renal failure. In both humans and rodents toxicity begins with a reactive metabolite that binds to proteins. This leads to mitochondrial dysfunction and nuclear DNA fragmentation resulting in necrotic cell death. Pleurotus ostreatus (an edible oyster mushroom) is well recognized as a flavourful food, as...

This is a report on photo-irradiated extracellular synthesis of silver nanoparticles using the aqueous extract of edible oyster mushroom (Pleurotus florida) as a reducing agent. The appearance, size, and shape of the silver nanoparticles are understood by UV-visible spectroscopy, field emission scanning electron microscopy, transmission electron microscopy, and atomic force microscopy. The X-ra...

Pleurotus florida produces two extracellular laccase (L1 and L2) isoenzymes and the L1 isoenzyme is dominantly involved in the dye decoloration process. L1 isoenzyme was successfully purified to 6.4 fold with a yield of 36% and had a specific activity of 52.6 U mg of protein. The purified laccase was monomeric with an apparent molecular mass of ≈54 kDa. The optimum pH and temperature of the LI ...

Greenhouse experiment was conducted for four months using Leucaena leucocephala and Pleurotus tuber-regium to determine their bioremediation potentials. Leucaena leucocephala, Pleurotus tuber-regium and Leucaena leucocephala combined with Pleurotus tuber-regium were tested for their ability to improve nutrient (N, P, K, total organic carbon) and reduce heavy metals (Zn, Ni, Pb, Cu) of soil poll...