نتایج جستجو برای: platelet disorder
تعداد نتایج: 699157 فیلتر نتایج به سال:
Summary: Chronic immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a low platelet count that has persisted for more than 12 months. Patients may be asymptomatic but those with severe, disease may have significant morbidity and require treatment. Historically, the pathogenesis of ITP was believed to be increased platelet destruction by anti-platelet antibodies. Treatment o...
RUNX1 gene alterations are associated with acquired and inherited hematologic malignancies that include familial platelet disorder/acute myeloid leukemia, primary or secondary acute myeloid leukemia, and chronic myelomonocytic leukemia. Recently, we reported that RUNX1-mediated silencing of nonmuscle myosin heavy chain IIB (MYH10) was required for megakaryocyte ploidization and maturation. Here...
Bernard-Soulier syndrome is an inherited platelet disorder, which is transmitted in an autosomal recessive manner. This syndrome is characterized by variable thrombocytopenia and large defective platelets. Bernard-Soulier syndrome often presents early with bleeding symptoms, such as epistaxis, ecchymosis, menometrorrhagia, and gingival or gastrointestinal bleeding. Diagnosis can be confirmed by...
AIM The relationship between psychological stress and platelet activation has been widely studied. It is well known that platelets may reflect certain biochemical changes that occur in the brain when different mental conditions occur. Platelet 5-hydroxytryptamine (5-HT) is also extensively studied in psychiatry. The mean platelet volume (MPV), the accurate measure of platelet size, has been con...
Introduction: An inflammatory disorder known as lateral epicondylitis develops where the common extensor tendon of forearm originates over epicondyle. It is most prevalent chronic, debilitating, and painful elbow condition. 1 to 3 percent overall population experiences symptoms. Aim And Objectives: assess results a brief follow-up study after single dose autologous platelet-rich plasma injectio...
ITP is an autoimmune disorder, due to increased platelet destruction. This condition may be acute, chronic or recurrent. In the acute form, the platelet count returns to normal within 6 months after diagnosis. In the chronic form, the platelet count remains low beyond 6 months. In approximately 90% of children ITP is acute and self-limited disease. Splenectomy is indicated for severe acute ...
Many snake venom proteins have been isolated that affect platelet plug formation by interacting either with platelet integrins, membrane glycoprotein Ib (GPIb), or plasma von Willebrand factor (VWF). Among them, disintegrins purified from various snake venoms are strong inhibitors of platelet aggregation. Botrocetin and bitiscetin derived from Bothrops jararaca and Bitis arietans venom, respect...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید