The cholesteryl esters of very low density lipoproteins become labeled when human plasma is incubated with cholesterol-(14)C. The relative order of magnitude of the specific activity of the cholesteryl esters of the major lipoprotein fractions is: high density lipoproteins >> very low density lipoproteins > low density lipoproteins. This pattern of labeling is similar to that found by others in...

Phosphatidylethanol (PEth) is an abnormal phospholipid formed only in the presence of ethanol. Ethanol causes changes in the concentration and composition of plasma lipoproteins and it also influences the enzymes and transfer proteins that modify lipoproteins in plasma. PEth might be one of these changes brought on by ethanol in the circulation. The present study was designed to investigate whe...

The European badger has previously been shown to exhibit yearly cycles of locomotor activity, endocrine secretions, and body weight, as well as seasonal variations in plasma cholesterol. Over a period of 2 years, we have followed the plasma levels of free and esterified cholesterol, triglycerides and phospholipids, and of plasma lipoproteins (by means of polyacrylamide gel electrophoresis, agar...

The physiological significance of sphingosine 1-phosphate (S1P) transport in blood has been debated. We have recently reported a comprehensive sphingolipid profile in human plasma and lipoprotein particles (VLDL, LDL, and HDL) using HPLC-MS/MS (Hammad et al., 2010). We now determined the relative concentrations of sphingolipids including S1P in the plasma subfraction containing lipoproteins com...

The possible role of human plasma lipoproteins as car riers in the transport of the carcinogen, benzo(a)pyrene, was assessed in in vitro studies. [14C]Benzo(a)pyrene was incubated in whole human blood, plasma, or isolated lipo protein fractions. Benzo(a)pyrene d istribution between plasma and red blood cells was estimated following sedi mentation of red blood cells. Benzo(a)pyrene distribution ...