نتایج جستجو برای: placebo phenomenon

تعداد نتایج: 224637  

Journal: :Gut 1988
T Rokkas C Pursey E Uzoechina L Dorrington N A Simmons M I Filipe G E Sladen

This double blind randomised study tested the effectiveness of colloidal bismuth subcitrate (De-Nol) in non-ulcer dyspepsia (NUD) and if any benefit is associated with clearance of Campylobacter pylori (C pylori) from the gastric mucosa. Sixty six patients with dyspepsic symptoms, normal abdominal ultrasound, and upper GI endoscopy, were randomly allocated to placebo or De-Nol for eight weeks. ...

Journal: :Journal of applied physiology 2010
Joel D Trinity Matthew D Pahnke Joshua F Lee Edward F Coyle

People who become hyperthermic during exercise display large increases in heart rate (HR) and reductions in stroke volume (SV). It is not clear if the reduction in SV is due primarily to hyperthermia or if it is a secondary effect of an elevation in HR reducing ventricular filling. In the present study, the upward drift of HR during prolonged exercise was prevented by a very small dose of the β...

2016
Chris G. McMahon

Large well-designed clinical efficacy and safety randomized clinical trials (RCTs) are required to achieve regulatory approval of new drug treatments. The objective of this article is to make recommendations for the criteria for defining and selecting the clinical trial study population, design and efficacy outcomes measures which comprise ideal premature ejaculation (PE) interventional trial m...

2016
Md. Sahab Uddin Abdullah Al Mamun Md. Asaduzzaman Md. S. Uddin

In terms of advancement of life to meet the challenges new method for neuropsychopharmacological research are continually developing to ensure superior safety, accuracy, efficacy, precision etc. In this experiment, we suggested and validated two neuropsychopharmacological testing methods, these are Numeral Finding (NF) and Typo Revealing (TR) tests for the determination of attention in healthy ...

2014
Patrick A. McConnell Brett Froeliger Eric L. Garland Jeffrey C. Ives Gary A. Sforzo

Binaural beats are an auditory illusion perceived when two or more pure tones of similar frequencies are presented dichotically through stereo headphones. Although this phenomenon is thought to facilitate state changes (e.g., relaxation), few empirical studies have reported on whether binaural beats produce changes in autonomic arousal. Therefore, the present study investigated the effects of b...

2013
Marco Annoni

In the last 30 years, a converging series of laboratory experiments, clinical trials, and neurocognitive studies have identified several key mechanisms of placebo effects. These studies suggest not only that placebo responses may be ubiquitous across research and clinical settings, but also that they can significantly modulate symptoms across a wide spectrum of highly prevalent conditions such ...

2016
Erik Stroes John R. Guyton Norman Lepor Fernando Civeira Daniel Gaudet Gerald F. Watts Marie T. Baccara‐Dinet Guillaume Lecorps Garen Manvelian Michel Farnier K. Kostner S. Lehman O. Descamps L. Gheyle C. Mathieu J. Bergeron T. Elliott G. Girard A. Gupta G. Hoag J. Hove J. Jeppesen J.H. Kjærulf K. Klarlund K.K. Thomsen D.C.G. Basart A. Kooy A. Liem H. Swart R. Troquay J Van Het Hof‐Wiersma P. Viergever F. Visseren R.N. Doughty R. Scott C. Calvo J.L. Díaz‐Díaz F. Fuentes B. Gil‐Extremera C. Jericó L. Matas Pericas J.D. Mediavilla Garcia D.E. Bolster M. Koren M. El Shahawy G. Vardi D. Weinstein K. Zuzarte Henry Ginsberg Jennifer G. Robinson Daniel J. Rader Christopher P. Cannon Helen Colhoun John J.P. Kastelein Yong Huo Anders Olsson David Waters Dominique Larrey Robert S. Rosenson Peter A. Patriarca Geert Molenberghs Pierluigi Tricoci Kenneth W. Mahaffey Renato D. Lopes Bimal R. Shah Rajendra H. Mehta Matthew T. Roe Zubin Eapen Luciana Armaganijan Adriana Bertolami Sergio Leonardi Bradley J. Kolls J. Dedrick Jordan Grégory Ducrocq Etienne Puymirat Robin Mathews

BACKGROUND The PCSK9 antibody alirocumab (75 mg every 2 weeks; Q2W) as monotherapy reduced low-density lipoprotein-cholesterol (LDL-C) levels by 47%. Because the option of a monthly dosing regimen is convenient, ODYSSEY CHOICE II evaluated alirocumab 150 mg Q4W in patients with inadequately controlled hypercholesterolemia and not on statin (majority with statin-associated muscle symptoms), rece...

Journal: :Cephalalgia : an international journal of headache 2015
Knut Hagen Eiliv Brenner Mattias Linde Gøril Bruvik Gravdahl Erling Andreas Tronvik Morten Engstrøm Ursula Sonnewald Grethe Helde Lars Jacob Stovner Trond Sand

BACKGROUND Preventive medication is indicated for many migraine patients, but is used in relatively few. The aim of the present study was to evaluate the efficacy of acetyl-l-carnitine as a prophylactic drug in migraine patients. METHODS A single-center, randomized, triple-blind, placebo-controlled, crossover study was carried out. Men and women, age 18-65 years, with episodic migraine but ot...

1995
P. Usha Rani M.U.R. Naidu G.A. Rama Raju G. Shobha T. Ramesh Kumar Rao J.C. Shobha T. Vijay Kumar

Efficacyand safety of a new herbal cream containing aqueous extracts of Azadirachta indica, Curcuma longa, Pongamia glabra, Glycyrrihiza glabra and Santallum album were evaluated in amulticentric, randomized, double-blind, placebo-controlled study. With active drug treatment, there was significant improvement in various signs like redness, oedema and symptoms like itching, burning, discharge an...

Journal: :journal of reproduction and infertility 0

background: premenstrual syndrome (pms) is a condition characterized by a number of behavioral, psychological and physical symptoms recurring cyclically during the luteal phase of the menstrual cycle. the uncertainty in the pathogenesis of pms has led to many treatment protocols being suggested as possible therapies. the present study was carried out to compare the effects of echinophora-platyl...

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