The performance of future linear colliders are limited by the effect of short-range collimator wakefields on the beam. The beam quality is sensitive to the positioning of collimators at the end of the linac. The determination of collimator wakefields has been difficult, largely because of the scarcity of measurement data, and of the limitation of applicability of analytical results to realistic...

The use of a multileaf collimator in the dynamic mode to perform intensity modulated radiotherapy became a reality at our institution in 1995. Unlike treatment with static fields using a multileaf collimator, there are significant dosimetric issues which must be assessed before dynamic therapy can be implemented. We have performed a series of calculations and measurements to quantify head scatt...

In October 2009, a quad, mini-beam collimator was implemented at GM/CA CAT that allowed users to select between a 5, 10, or 20 micron mini-beam or a 300 micron scatter guard for macromolecular crystallography [1]. Initial alignment of each pinhole to the optical axis of each path through the mini-beam collimator is performed under an optical microscope using an alignment jig. Next, the pre-alig...

PURPOSE AND METHODS The noninvasive microsphere (NIMS) method quantifies cerebral blood flow with N-isopropyl-p-[123I]-iodoamphetamine (123I-IMP) without blood sampling of a patient, but when a fan beam collimator is used for collecting raw data in single photon emission computed tomography (SPECT), the procedure is complicated because we have to change the collimator. In phantom and clinical s...

BACKGROUND Scintillation camera imaging is used for treatment planning and post-treatment dosimetry in liver radioembolization (RE). In yttrium-90 (90Y) RE, scintigraphic images of technetium-99m (99mTc) are used for treatment planning, while 90Y Bremsstrahlung images are used for post-treatment dosimetry. In holmium-166 (166Ho) RE, scintigraphic images of 166Ho can be used for both treatment p...

Background. Although heart-to-mediastinum (H/M) ratio in a planner image has been used for practical quantification for I-metaiodobenzylguanidine (MIBG) imaging, standardization of the parameter is not yet established. We hypothesized that the value of H/M can be standardized to the various types of camera-collimator combinations. Methods and Results. Standard phantoms consisting of the heart, ...

We present an automatic method that can be used to abstract high resolution images into very low resolution outputs with reduced color palettes in the style of pixel art. Our method simultaneously solves for a mapping of features and a reduced palette needed to construct the output image. The results are an approximation to the results generated by pixel artists. We compare our method against t...

This paper considers the ubiquitous problem of estimating the state (e.g., position) of an object based on a series of noisy measurements. The standard approach is to formulate this problem as one of measuring the state (or a function of the state) corrupted by additive Gaussian noise. This model assumes both (i) the sensor provides a measurement of the true target (or, alternatively, a separat...

We demonstrate a new type of spatial phase-shifting, dynamic interferometer that can acquire phase-shifted interferograms in a single camera frame. The interferometer is constructed with a pixelated phase-mask aligned to a detector array. The phase-mask encodes a high-frequency spatial interference pattern on two collinear and orthogonally polarized reference and test beams. The phase-differenc...