Autoimmune hypothyroidism is a common medical condition. Its revelation by thyrotrophic hyperplasia is an unusual and may be misdiagnosed as a pituitary adenoma. A 35-year-old man is referred to us for endocrinological assessment before surgery of a pituitary macroadenoma with bitemporal hemianopsia. Biological data reveal profound primary hypothyroidism. With thyroid hormone substitution, the ...

AIM Total surgical resection of pituitary macroadenomas is difficult due to the location of the adenoma and the propensity to invade surrounding tissues. The purpose of this study was to evaluate the risk factors for invasive and aggressive pituitary macroadenomas using radiological, hormonal, clinical, and immunohistochemical markers. MATERIAL AND METHODS Seventy cases of pituitary macroaden...

The posterior lobe is an extension of the hypothalamus and secretes two hormones: antidiuretic hormone (or arginine vasopressin) and oxytocin. The pituitary stalk and the portal vessel pass through a small diaphragm that separates the sella turcica from the middle fossa. This anatomic arrangement places the pituitary at risk for infarction or hemorrhage when a mass increases pressure in the sel...

We discuss a complicated case of a 34 year-old male with cutis verticis gyrata presenting simultaneously with hypertrophic osteoarthropathy and a pituitary macroadenoma. The patient was initially suspected of having acromegaly secondary to the pituitary adenoma but further workup showed normal insulin growth factor-1 and growth hormone levels inconsistent with acromegaly. Subsequent workup was ...

We report a young woman with spontaneous ovarian hyperstimulation syndrome (OHSS), headaches, visual field defect and pituitary macroadenoma. She underwent transsphenoidal surgery with remission of OHSS. Immunohistochemical staining was positive for β-FSH and β-LH. Recurrence occurred after four years. The patient was treated with octreotide administration and conventional radiation therapy. Oc...

Pituitary apoplexy is a serious condition, which if left untreated, might lead to irreversible life-long complications. Hence, pituitary should always be included in the differential diagnoses of patient with an isolated sixth cranial nerve (CN) palsy. This report highlights case presenting CN palsy associated apoplexy. Although adenomas are common, they seldom present abducent without any othe...

Abstract Introduction: Diabetes insipidus (DI) rarely occurs in pituitary tumors although some patients may develop DI following tumor resection. However is known to occur with metastatic the or infiltrative disorders of gland. We are reporting a patient 2 cm macroadenoma whose was unmasked by glucocorticoid therapy. Case Presentation: A 61-year-old male history non-functioning macroadenoma, in...