The homeodomain protein Pit-1 cooperates with the basic-leucine zipper protein CCAAT/enhancer binding protein alpha (C/EBPalpha) to control pituitary-specific prolactin gene transcription. We previously observed that C/EBPalpha was concentrated in regions of centromeric heterochromatin in pituitary GHFT1-5 cells and that coexpressed Pit-1 redistributed C/EBPalpha to the subnuclear sites occupie...

In this study, a hybrid intelligent model has been designed to predict groundwater inflow to a mine pit during its advance. Novel hybrid method coupling artificial neural network (ANN) with genetic algorithm (GA) called ANN-GA, was utilised. Ratios of pit depth to aquifer thickness, pit bottom radius to its top radius, inverse of pit advance time and the hydraulic head (HH) in the observation w...

The homeodomain (HD) protein Pit-1 cooperates with the basic-leucine zipper (b-ZIP) protein CCAAT/enhancer binding protein alpha (C/EBPα) to control pituitary-specific prolactin (PRL) gene transcription. We previously observed that C/EBPα was concentrated in regions of centromeric heterochromatin in pituitary GHFT1-5 cells and that co-expressed Pit-1 redistributed C/EBPα to the subnuclear sites...

Peptide immunotherapy (PIT) offers realistic prospects for the treatment of allergic diseases, including allergic asthma. Much is understood of the behavior of naive T cells in response to PIT. However, treatment of patients with ongoing allergic disease requires detailed understanding of the responses of allergen-experienced T cells. CD62L expression by allergen-experienced T cells corresponds...

This paper provides nested sets and vector representations of knockout tournaments. The paper introduces classification of probability domain assumptions and a new set of axioms. Two new seeding methods are proposed: equal gap seeding and increasing competitive intensity seeding. Under different probability domain assumptions, several axiomatic justifications are obtained for equal gap seeding....

A novel rotor was constructed to allow for the seeding of porous scaffolds via centrifugal force. Using cell seeding times of 10 min, this method placed significantly (roughly 3-fold) more cells into poly(glycolic acid) scaffolds than 24 h of spinner flask seeding or static seeding. There were no significant differences in the mitochondrial activity per cell between the 3 seeding methods. Cell ...

The usefulness of magnifying endoscopy was assessed by examining the extent to which a magnifying endoscope can provide images of pits and by analyzing the consistency of the pit patterns visualized by magnifying endoscopy with the pit patterns visible under a stereomicroscope. Study materials consisted of 83 cases of tumorous colorectal lesions. Under a magnifying endoscope, pits were visible ...

BACKGROUND Pavlovian processes are thought to play an important role in the development, maintenance and relapse of alcohol dependence, possibly by influencing and usurping ongoing thought and behavior. The influence of pavlovian stimuli on ongoing behavior is paradigmatically measured by pavlovian-to-instrumental transfer (PIT) tasks. These involve multiple stages and are complex. Whether incr...