GH expression in mammary tumors has been related to the increase and spreading of cell proliferation. Using the MCF-7 human breast adenocarcinoma cell line, it has been demonstrated that autocrine GH-stimulated mammary carcinoma cell proliferation decreased the apoptosis rate and enhanced cell spreading. Surprisingly, no data are available about the presence of Pit-1 (the main pituitary regulat...

The key feature of the pit is that they are bounded below by 0 and above by 1. Thus we are guaranteed that all moments of (p1t, ..., pIt) exist for all data-generating processes for the nominal price vector (P1t, ..., PIt), something that is not true of (q1t, ..., qIt). This means that one can use moments to summarise the features of (p1t, ..., pIt), something that we cannot be assured is valid...

Introduction: Pit craters are circular to elliptical collapse features that commonly occur in alignments (chains) and that coalesce into troughs [1], [2], [3], [4], [5]. We have begun systematically mapping the regional distribution of pit chains in the western hemisphere of Mars using the Mars Orbiter Camera (MOC) data. Pit chains are most prominent in the Alba Patera region and along the Vall...

one of the main concerns of the mining industry is to determine ultimate pit limits. final pit is a collection of blocks, which can be removed with maximum profit while following restrictions on the slope of the mine’s walls. the size, location and final shape of an open-pit are very important in designing the location of waste dumps, stockpiles, processing plants, access roads and other surfac...

background: sacral pit is a shallow or deep dimple in the lower sacral region, with a reported prevalence of 3-5% among newborns. the aim of the present study was to investigate spinal cord abnormalities in newborns with sacral pit via ultrasound examinations. methods: in this descriptive study, 3071 infants born at 34-42 weeks of gestation were studied in hospitals affiliated to islamic azad u...

AIM Triple-negative breast cancer (TNBC) is considered one of the most aggressive subtypes of breast cancer. Near infrared photoimmunotherapy (NIR-PIT) is a cancer treatment that employs an antibody-photosensitizer conjugate (APC) followed by exposure of NIR light for activating selective cytotoxicity on targeted cancer cells and may have application to TNBC. In order to minimize the dose of AP...

INTRODUCTION Emergency department (ED) crowding negatively impacts patient care quality and efficiency. To reduce crowding many EDs use a physician-in-triage (PIT) process. However, few studies have evaluated the effect of a PIT processes on resident education. Our objective was to determine the impact of a PIT process implementation on resident education within the ED of an academic medical ce...

Tests of Pavlovian-instrumental transfer (PIT) demonstrate that reward-predictive stimuli can exert a powerful motivational influence on the performance of instrumental actions. Recent evidence suggests that predictive stimuli produce this effect through either the general arousal (general PIT) or the specific predictions (outcome-specific PIT) produced by their association with reward. In two ...

"Pitted" red cell counts (pit counts) were performed serially during a period of 18 months in 130 Jamaican children with homozygous sickle cell (SS) disease aged 0-4 years. Raised pit counts, defined as 10% or more "pitted" red cells, were present in 23% of the children at age 12 months, in 42% at age 24 months, and in 52% at age 36 months. Radioactive colloid spleen scans showed no splenic upt...