The extraordinary level of accumulation of nickel (Ni) in hyperaccumulator plants is a consequence of specific metal sequestering and transport mechanisms, and knowledge of these processes is critical for advancing an understanding of transition element metabolic regulation in these plants. The Ni biopathways were elucidated in three plant species, Phyllanthus balgooyi, Phyllanthus securinegioi...

In the present investigation the antimutagenic effects of Phyllanthus fruit extract (PFE) has been evaluated against cyclophosphamide induced genotoxicity in bone marrow cells of mice. The administration of Phyllanthus fruit extract at various doses i.e. 170, 340 and 680 mg /kg . When treated individually did not induce chromosomal aberrations in somatic cells of mice(24 hr). A single Intra per...

The antibacterial and antifungal activities of Phyllanthus acidus was investigated against S.aureus (gram+ve), E.coli (gram-ve) and C.albicans using the Stokes disc diffusion, the Pour plate, Well diffusion and Streak plate methods. The solvent type extracts were obtained by three extractions with hexane, CH2Cl2, EtOAc and CH3CH2OH respectively. Solvents were removed in vacuo to yield viscous o...

Our research studies data suggest that, there were significant variations in the observed biochemical parameters. The level of TBARS in ethanol intoxicated rats increased two fold when compared with the control animals. The levels of GSH, SOD and CAT decreased significantly in the ethanol intoxicated rats. The level of GPx was increased in the ethanol intoxicated rats. The value of vitamin E in...

Phyllanthus amarus Schum. Thonn. is an indigenous medicinal plant, which has a folk reputation in central and southern India as hypoglycemic agent. The present investigation was carried out to evaluate the antidiabetic effect of ethanolic leaf extract of Phyllanthus amarus in alloxan induced diabetic mice. Blood glucose levels and body weights of control and diabetic mice were monitored. In the...

The optimal conditions for preparation of total phenolic acids in Phyllanthus emblica, and to study their inhibitory effect on human hepatoma cells have been investigated. The conditions for extraction of phenolic acid constituents in Phyllanthus emblica were investigated, and single factor and orthogonal tests were performed on conditions such as extraction solvent, extraction temperature, ext...

The aqueous extract of Phyllanthus amarus Schum & Thorn, was selected for preliminary phytochemical and antibacterial activity against human pathogens. Minimum inhibitory concentration was performed by broth dilution method and the zone of inhibition was studied by agar disc diffusion method at concentrations of 10 and 20 mg/ml in DMSO (Dimethyl Sulfoxide). The results revealed the antimicrobia...

In the present study the effect of alcholic extract of the Phyllanthus niruri whole plant on rat biochemical and serum marker enzymes against Staphylococcus aureus induced oxidative stress in the rat liver. Pre and post-treatment with extract showed a dose-dependent reduction of Staphylococcus aureus induced rats were elevated levels of enzyme activity with parallel increase in total protein an...

The antimicrobial potential of seventy-seven extracts from twenty-four plants was screened against eight bacteria and four pathogenic fungi, using microbroth dilution assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Water extracts of Acacia nilot...

Impact of Phyllanthus amarus extract on antioxidant enzymes in Drosophila melanogaster N. Manasa, J. S. Ashadevi