A gene cluster responsible for the biosynthesis of squalestatin S1 (SQS1, 1) was identified by full genome sequencing of two SQS1-producing ascomycetes: Phoma sp. C2932 and unidentified fungus MF5453. A transformation protocol was established and a subsequent knockout of one PKS gene from the cluster led to loss of SQS1 production and enhanced concentration of an SQS1 precursor. An acyltransfer...

The aim of this study was to identify the endophytic fungi from medicinal plant Ricinus communis and to investigate their potential antibacterial activity. 10 fungal species of endophytic fungi were successfully isolated from Ricinus communis including Aspergillus fumigates, Aspergillus japonicas, Aspergillus niger, Fusarium semitectum, Curvularia pallescens, Phoma hedericola, Alternaria tenuis...

Endophytic fungi are rich in species diversity and may play an important role in the fitness of their host plants. This study investigated the diversity and antimicrobial potential of endophytic fungi obtained from Saussurea involucrata KAR. et KIR. A total of 49 endophytic fungi were isolated from S. involucrata and identified using morphological and molecular techniques. Extracts of fermentat...

Three new diphenyl ether derivatives-phomaethers A-C (1-3) and five known compounds-including a diphenyl ether analog, 2,3'-dihydroxy-4-methoxy-5',6-dimethyl diphenyl ether (4); and four isocoumarin derivatives, diaportinol (5), desmethyldiaportinol (6), citreoisocoumarinol (7), and citreoisocoumarin (8)-were isolated from a gorgonian-derived fungus Phoma sp. (TA07-1). Their structures were elu...

Recently, we found that fungi are involved in breaking seed dormancy of Opuntia streptacantha, and that the effect of fungi on seeds is species-specific. However, the effect of fungi on seed germination from other Opuntia spp has not been evaluated. Thus, we evaluated the effect of four fungal species (Penicillium chrysogenum, Phoma sp., Trichoderma harzianum, Trichoderma koningii) on the germi...

Potato (Solanum tuberosum) is a valuable cultivated vegetable with high nutritional qualities containing variety of essential ingredients such as starch, vitamins and minerals. However cultivating potatoes significantly complicated by diseases caused number phytopathogens both bacterial fungal nature. Phytophthora infestan s, Alternaria sp., Phoma exigua , Rhizoctonia solani, Fusarium Verticill...