Str. Case [+SC +HR –LR ] [+SC –HR –LR ] [–SC –HR +LR ] Morph. Str. Case [ ] [–HR,–LR] — Abstract case features function as constraints on morphosyntactic case. A theta-role’s abstract case must optimally match the argument’s morphosyntactic case. Because they are categorized by the same features, the relation between these two levels of representation can be established by general principlescas...

ro is the acquisition of protective barrier function in the skin a process involving differentiation of keratinocytes to form a stratum corneum of unique lipid composition and structure. Harlequin Ichthyosis (HI) is a severe hyperkeratotic skin disease caused by mutations in the ABCA12 transport protein and which results in profound barrier defects. In keratinocytes ABCA12 is thought to regulat...

BACKGROUND Spine deformity can be idiopathic (more than 80% of cases), neuromuscular, congenital or neurofibromatosis-related. However, there are many disorders that may also be involved. We present our experience treating patients with scoliosis or other spine deformities related to rare clinical entities. METHODS A retrospective study of the records of a school-screening study in North-West...

Thalidomide remains one of the world’s most notorious drugs due to the severe birth defects it induced in children between 1957 and 1962. Yet, to some this drug is a lifesaver, as it now enjoys renaissance in the treatment for a wide range of conditions including leprosy, multiple myeloma, Behcet’s disease, and some cancers. However, thalidomide has also been linked to causing a new generation ...

BACKGROUND Reports of malformed frogs have increased throughout the North American continent in recent years. Most of the observed malformations have involved the hind limbs. The goal of this study was to accurately characterize the hind limb malformations in wild frogs as an important step toward understanding the possible etiologies. METHODS During 1997 and 1998, 182 recently metamorphosed ...

Development of epilepsy services in the northern region has included a baseline audit of the availability of pre-conceptual advice, AED prescribing, folic acid usage, vitamin K administration and pregnancy outcome in women with epilepsy which we now report. Patients, identified by community midwives, complete a standardized interview questionnaire with a research nurse. Delivery outcome is reco...

Twenty children attending the Princess Margaret Rose Orthopaedic Hospital, Edinburgh, need a powered upper limb prosthesis. These children have the now familiar range of upper limb disabilities, from bilateral amelia to bilateral phocomelia, due to thalidomide. They were born between 1960 and 1962. Before the task of fitting the first children was begun, the main centres in Germany were visited...