نتایج جستجو برای: phenotypic activity
تعداد نتایج: 1188591 فیلتر نتایج به سال:
BACKGROUND X-linked Charcot-Marie-Tooth disease type 5 (CMTX5), Arts syndrome, and non-syndromic sensorineural deafness (DFN2) are allelic syndromes, caused by reduced activity of phosphoribosylpyrophosphate synthetase 1 (PRS-I) due to loss-of-function mutations in PRPS1. As only few families have been described, knowledge about the relation between these syndromes, the phenotypic spectrum in p...
AIMS NADPH oxidase (NOX) is the primary source of reactive oxygen species (ROS) in vascular smooth muscle cells (SMC) and is proposed to play a key role in redox signaling involved in the pathogenesis of cardiovascular disease. Growth factors and cytokines stimulate coronary SMC (CSMC) phenotypic modulation, proliferation, and migration during atherosclerotic plaque development and restenosis. ...
The natural distribution and the species ecology of lesser-known nocturnal endemic brown palm civet in Western Ghats are definite. We used camera trap data from to predict suitable niche, coat colour pattern, diel activity. environmental variables like rainfall, elevation, isothermaility, tree density, height profoundly influence civet’s habitat suitability. determined that most area entire is ...
Prolonged sitting appears to accelerate aging, while optimal physical activity patterns have been found delay the process. It is an emerging topic, and no conclusions reached regarding relationship between biomarkers-measured aging. Hence, aim of this study was investigate association sensor-based objectively measured phenotypic age using a nationwide population from National Health Nutrition E...
Covarying phenotypic traits can limit natural selection’s ability to modify these traits. Most evolutionary studies on trait covariation use the comparative method to study complex traits of multicellular organisms. Simpler traits have the advantage of being amenable to experimental evolution. Here we study such a simple molecular system, the TEM-1 beta-lactamase protein, a promiscuous enzyme t...
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