*Corresponding Author: Dr. S.K. Singh, Senior Principal Scientist and In-charge, Pharmacokinetics & Metabolism Division, Central Drug Research Institute, Lucknow, India. 3122 MULTIPLE-DOSE PHARMACOKINETICS OF A NOVEL, SYNTHETIC TRIOXANE-ANTIMALARIAL COMPOUND 97/78 IN RATS USING LC-MS/MS METHOD Rajendra Pratap Singh, S Sabarinath, Hari Narayan Kushwaha, Nagsen Gautam, Ram Chandra Gupta and Shio ...

Carbamazepine is widely used for the treatment of epilepsy, trigeminal neuralgia and psychiatric disorders. However, therapy often ineffective, some patients experience adverse drug reactions, which negatively affect both efficacy safety therapy.
 This review systematized presented up-to-date information regarding pharmacokinetics pharmacogenetics carbamazepine, as well most common reactio...

Background: Although aminoglycosides are often used as treatment for Gram-negative infections, optimal dosing regimens remain unclear, especially in ICU patients. This is due to a large between- and within-subject variability the aminoglycoside pharmacokinetics this population. Objective: review provides comprehensive data on of patients hospitalized by summarizing all published PopPK models am...