The number of imaging data sets has significantly increased during radiation treatment after introducing a diverse range of advanced techniques into the field of radiation oncology. As a consequence, there have been many studies proposing meaningful applications of imaging data set use. These applications commonly require a method to align the data sets at a reference. Deformable image registra...

BACKGROUND A tissue-mimicking phantom that accurately represents human-tissue properties is important for safety testing and for validating new imaging techniques. To achieve a variety of desired human-tissue properties, we have fabricated and tested several variations of gelatin phantoms. These phantoms are simple to manufacture and have properties in the same order of magnitude as those of so...

We have developed a phantom manufactured with thin film techniques that enables precise placement of sub-resolvable "digital scatterers" on an acoustically transparent supporting medium within the scan plane of an ultrasound system. This technique permits formation of sophisticated test targets commonly used in imaging science. These phantoms can reveal the combined influence of all the stages ...

Certain diseases produce changes in the elastic properties of soft tissues. Conventional imaging modalities in some cases have poor performance in diagnosing these types of diseases. To overcome this problem, elastographic imaging techniques that focus on evaluating the elastic properties of tissues, i.e., tissue stiffness, have been developed in the past three decades. Soft tissues, however, i...

Line-field confocal optical coherence tomography (LC-OCT) is an imaging modality based on a combination of time-domain and reflectance microscopy. LC-OCT provides three-dimensional images semi-transparent samples with spatial resolution ∼ 1 μm. The technique primarily applied to in vivo skin imaging. image contrast arises from the backscattering incident light by sample microstructures, which d...

We evaluated dual-echo Dixon in-phase and out-of-phase (IP-OP), chemical shift imaging (CSI), and (1)H MRS (hydrogen MR spectroscopy) in estimating fat content (FC) in phantoms and in livers of mice. Phantoms were made according to the volume percentage of fat ranging from 0% to 100%. The three MR methods were performed to measure FC in phantoms and in livers of obese leptin-deficient (ob/ob), ...

In optical coherence tomography (OCT), axial resolution is one of the most critical parameters impacting image quality. It is commonly measured by determining the point spread function (PSF) based on a specular surface reflection. The contrast transfer function (CTF) provides more insights into an imaging system's resolving characteristics and can be readily generated in a system-independent ma...

This paper presents an initial implementation of a Virtual Ultrasound Imaging System as an interactive educational tool for students and researchers in the medical ultrasound imaging field. The system uses a cause and effect approach for understanding the results of changing transducer attributes and pulse parameters on the quality of the ultrasound image. The elements of the system include Fie...

Abstract Phantoms are commonly used throughout medical imaging and physics for a multitude of applications, the designs which vary between modalities clinical or research requirements. Within positron emission tomography (PET) nuclear medicine, phantoms have well-established role in validation protocols so as to reduce administration radioisotope volunteers. Similarly, within magnetic resonance...