UNLABELLED This article demonstrates resolution recovery in 18F SPECT image reconstruction by using an iterative algorithm that corrects for the system geometric response. METHODS Patient and phantom studies were performed using a Picker PRISM 3000 three-detector SPECT system (Picker International, Inc., Cleveland, OH) to image 18F with 511 keV collimators. A measured point response function ...

Nowadays multi-modality imaging has gained great interest in biology research by offering complementary information. In this paper, a modularly designed fluorescence molecular tomography (FMT) system has been developed, which can be not only used as a standalone imaging device, but also feasibly integrated with other imaging modalities, such as X-ray computed tomography (X-CT), single photon em...

OBJECTIVE To devise and validate a method of estimating accurately myocardial wall thickness from cardiac images acquired with single photon emission tomography (SPECT). MATERIALS AND METHODS We simulated the imaging process by convolving a spatial resolution function, experimentally determined for a clinical SPECT system, with rectangular profiles mimicking the myocardial walls for different...

introduction: it is a common protocol to use 201tl for the rest and 99mtc for the stress cardiac spect imaging. theoretically, both types of imaging may be performed simultaneously using different energy windows for each radionuclide. however, a potential limitation is the cross-contamination of scattered photons from 99mtc and collimator x-rays into the 201tl energy window. we used a middle en...

objective(s): the energy resolution of a cadmium-zinc-telluride (czt) solid-state semiconductor detector is about 5%, and is superior to the resolution of the conventional anger type detector which is 10%. also, the window width of the high-energy part and of the low-energy part of a photo peak window can be changed separately. in this study, we used a semiconductor detector and examined the ef...

OBJECTIVE We examined the difference of the effect by data to revise a gamma camera difference. The difference-correction method of the camera is incorporated in eZIS analysis. METHODS We acquired single photon emission computed tomography (SPECT) data from the three-dimensional (3D) Hoffman brain phantom (Hoffman), the three-dimensional brain phantom (3D-Brain), Pool phantom (pool) and from ...

Movement of the patient during myocardial perfusion SPECT leads to some artifacts that make the interpretation difficult. In this study, myocardial perfusion imaging protocol was performed on a cardiac phantom and SPECT was performed by simulating patient movements. A lesion model with dimensions of 1.2 × 2 × 2 cm was created on the inferoseptal wall of the cardiac phantom. Imaging was done in ...

BACKGROUND Hybrid imaging combines nuclear medicine imaging such as single photon emission computed tomography (SPECT) or positron emission tomography (PET) with computed tomography (CT). Through this hybrid design, scanned patients accumulate radiation exposure from both applications. Imaging modalities have been the subject of long-term optimization efforts, focusing on diagnostic application...

PURPOSE A phantom study was conducted to evaluate the feasibility of body contour definition with Compton scatter photons from external sources of technetium-99m pertechnetate (Tc-99m) to create a fusion image of CT and SPECT images. METHODS External sources of 1 mCi (37 MBq) Tc-99m were placed on each collimator, and body-contour SPECT images were obtained with an energy window of 100 keV +/...

A novel small-animal SPECT imager, FastSPECT II, was recently developed at the Center for Gamma-Ray Imaging. FastSPECT II consists of two rings of eight modular scintillation cameras and list-mode data-acquisition electronics that enable stationary and dynamic imaging studies. The instrument is equipped with exchangeable aperture assemblies and adjustable camera positions for selections of magn...