نتایج جستجو برای: pgr
تعداد نتایج: 1018 فیلتر نتایج به سال:
BACKGROUND The discordance in oestrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor 2 (HER2) status between primary and recurrent breast cancer is being intensively investigated and a large amount of data have been produced. However, results from different studies are heterogeneous and often conflicting. To highlight this issue, a meta-analysis of publi...
The zebrafish nuclear progestin receptor (nPR; official symbol PGR) was identified and characterized to better understand its role in regulating reproduction in this well-established teleost model. A full-length cDNA was identified that encoded a 617-amino acid residue protein with high homology to PGRs in other vertebrates, and contained five domains characteristic of nuclear steroid receptors...
Colon muscle strips and cells from female patients with slow-transit constipation (STC) exhibit impaired motility, signal transduction abnormalities characterized by downregulation of Gq/11 and upregulation of Gs proteins, decreased cyclooxygenase (COX)-1 and thromboxane (Tx)B2 levels, increased COX-2 and PGE2 levels, and overexpression of progesterone receptors (PGR). Progesterone (P4) treatme...
In this paper, we present Probabilistic Geographic Routing (PGR), a novel approach for the problem of power-aware routing in wireless ad hoc and sensor networks. Our protocol uses only local information to probabilistically forward the packet to the next hop. Every node relies on a beaconing process to keep track of the changes in the set of its neighbors. In order to forward a packet, the node...
We conducted a case-control study of estrogen receptor (ER) and progesterone receptor (PgR) expression in benign breast epithelium from 120 women (51 breast cancer cases and 69 benign disease controls) who underwent breast operations at University Hospital, Syracuse, New York. Benign samples were obtained and processed immunohistochemically for ER and PgR (Abbott, Chicago, IL). Receptor positiv...
Single progesterone receptor positive (PgRþ), especially in form of ER /PgRþ/HER2 , is a nonnegligible phenomenon. Little is known about the characteristics and the role of single PgR positive in this phenotype. Therefore, we explore the significance of single PgR positivity by comparing ER /PgRþ/HER2 breast cancers with triple negative breast cancers (TNBCs). Three thousand nine hundred sixty-...
PURPOSE To develop a guideline to improve the accuracy of immunohistochemical (IHC) estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer and the utility of these receptors as predictive markers. METHODS The American Society of Clinical Oncology and the College of American Pathologists convened an international Expert Panel that conducted a systematic review and eval...
Estrogen and progestin receptors (ER, PgR) play a critical role in the regulation of neuroendocrine functions in females. The neuroanatomical distribution of the recently cloned, ER , overlaps with both ER and PgR. To determine whether ER is found within ER or PgR-containing neurons in female rat, we used dual label immunocytochemistry. ER immunoreactivity (ER -ir) was primarily detected in the...
Endometrial cancer is the most common gynecological malignancy in Croatia. The aim of this study was to determine the immunohistochemical expression of estrogen receptors (ER) and progesterone receptors (PGR) in cancer cells and in the myometrium and to correlate it with prognostic factors of endometrial carcinoma. ER positivity in carcinoma cell nuclei was found in 42 cases (73.7%) and PGR pos...
Driving oxygen evolution reaction (OER) at extremely low overpotential and the blockage of gas inside catalytic material leads to deactivation activity, therefore it is an essential step in electrochemical energy conversion systems, but still very challenging task. The clay minerals including bentonite kaolinite are rich with plenty active centers favorable chemical composition for catalysis ap...
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