نتایج جستجو برای: peutz

تعداد نتایج: 822  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Chongjuan Wei Christopher I Amos Nianxiang Zhang Xiaopei Wang Asif Rashid Cheryl L Walker Richard R Behringer Marsha L Frazier

PURPOSE Peutz-Jeghers syndrome (PJS) is a unique disorder characterized by the development of hamartomas in the gastrointestinal tract as well as increased risks for variety of malignancies. Germ-line mutations of LKB1 cause PJS. We have generated Lkb1+/- mice, which model human PJS. Rapamycin and its analogues are promising preventive and therapeutic agents that specifically inhibit signaling ...

Journal: :Journal of the Royal Society of Medicine 1989

2017
Seungmin Ham Sarah J. Meachem Catherine S. Choong Adrian K. Charles Gareth S. Baynam Timothy W. Jones Nirukshi U. Samarajeewa Evan R. Simpson Kristy A. Brown

(2013). Overexpression of aromatase associated with loss of heterozygosity of the STK11 gene accounts for pepubertal gynecomastia in boys with Peutz-Jeghers Syndrome. Take down policy If you believe this document infringes copyright, raise a complaint by contacting [email protected]. The document will be immediately withdrawn from public access while the complaint is being investigated.

Journal: :Koloproktologiâ 2022

Introduction: Peutz-Jeghers syndrome (PEUTZ-JEGHERS SYNDROME; PJS; OMIM#175200) is hereditary tumor and characterized by the occurrence of hamartomatous polyps gastrointestinal tract, melanocytic pigmentation skin mucous membranes, as well a high predisposition to malignant tumors various locations. Despite fact that clinical features PJS are currently understood, nature variability in phenotyp...

Journal: :Japanese Journal of Oral & Maxillofacial Surgery 1973

Journal: :Journal of Korean Medical Science 1999

Journal: :Medical Journal Armed Forces India 1999

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