Over the past fifty years the processes and techniques of medical imaging have undergone a veritable explosion, calling into service increasingly sophisticated mathematical tools. Mathematics provides a language to describe the measurement processes that lead, eventually, to algorithms for turning the raw data into high-quality images. There are four principal modalities in wide application tod...

BACKGROUND: Attenuation correction is generally used to PET images to achieve count rate values independent from tissue densities. The goal of this study was to provide a qualitative comparison of attenuation corrected PET images produced by a PET-CT device (CT, 120 kV, 40 mAs, FOV 600 mm) with and without segmentation of transmission data (ACseg+ and ACseg-respectively). Methods: The reconstru...

Lung motion due to respiration causes image degradation in medical imaging, especially in nuclear medicine which requires long acquisition times. We have developed a method for image correction between the respiratory-gated (RG) PET images in different respiration phases or breath-hold (BH) PET images in an inconsistent respiration phase. In the method, the RG or BH-PET images in different resp...

Nowadays,it's still had to segment the Pulmonary nodules with others in PET-CT image. In this paper, to the Pulmonary nodules in PET-CT image, we use the method of LIBSVM to extract. As SVM having unique advantage in the problem of nonlinear identification, and there are more default parameters and less parameters adjustment in SVM when using LIBSVM, it's rapid and accurate to use LIBSVM to ext...

An important step in PET brain kinetic analysis is the registration of functional data to an anatomical MR image. Typically, PET-MR registrations in nonhuman primate neuroreceptor studies used PET images acquired early post-injection, (e.g., 0-10 min) to closely resemble the subject's MR image. However, a substantial fraction of these registrations (~25%) fail due to the differences in kinetics...

BODY: Objectives : A new F-18 agent for PET myocardial perfusion imaging (BMS747158) has been shown to have excellent image quality in a Phase I clinical trial. In a subgroup of patients undergoing imaging with this agent in a Phase II clinical trial, we assessed if dual gated perfusion study is feasible and leads to improved image quality. We generated motion free perfusion images by combining...

The purpose of this research is to establish an overall data set associated with the VOI (Volume of Interest), which is available for simultaneous assessment of PET/MRI and PET/CT regardless of the use of contrast media. The participants as objects of this investigation are 26 healthy examinees in Korea, SUV (standardized-uptake-value)s-maximum evaluation for whole-body F-18 FDG (fluorodeoxyglu...

PURPOSE To prospectively use compact avalanche photodiodes instead of photomultiplier tubes to integrate a positron emission tomographic (PET) detector and a 7-T magnetic resonance (MR) imager. MATERIALS AND METHODS All animal experiments were performed in accordance with the University of Tübingen guidelines and the German law for the protection of animals. A compact lutetium oxyorthosilicat...

Positron emission tomography (PET) scanners collect measurements of a patient’s in vivo radiotracer distribution. These measurements are reconstructed into cross-sectional images. Tomographic image reconstruction forms images of functional information in nuclear medicine applications and the same principles can be applied to modalities such as X-ray computed tomography. This chapter provides a ...