Summary The authors present 2 case reports of selective cefazolin hypersensitivity: a 49 year-old woman with a history of two perioperative reactions (urticaria and severe anaphylaxis) after the use of rocuronium, propophol and cefazolin; a 36 year-old pregnant woman who developed facial erythema, lips angioedema and hypotension immediately after administration of ropivacain, sufentanil, cefazo...

A 32-year-old 22-week pregnant hypertensive woman with sporadic episodes of headaches, sweating, and facial flushing was diagnosed with pheochromocytoma through biochemical and imaging tests. Perioperative management included a multidisciplinary approach, symptom stabilization with ɑ blockade followed by β blockade, and tumor resection by laparoscopic adrenalectomy at 24 weeks gestation. The di...

When undergoing chemotherapy, it is easy for patients to develop an intraoral disorder as an adverse event. If intraoral disorder worsens, we cannot but stop chemotherapy. In this situation, oral bacteria are often detected in the blood. The goal of perioperative oral function management (POMF) during chemotherapy is to allow chemotherapy to proceed smoothly while maintaining the intraoral envi...

references: 1. miller rd. miller’s anesthesia. 7th ed. philadelphia: churchill livingstone 2010 2758-9. 2. macintyre pe, schug sa, scott da, visser ej, walker sm. apm:se working group of the australian and new zealand college of anaesthetists and faculty of pain medicine. acute pain management: scientific evidence. 3rd ed. melbourne: anzca & fpm 2010 9-12. 3. buvanendran a. chronic postsurgical...

conclusions our new metabolic conditioning supplement, whether given pre- or postoperatively, led to better perioperative glycemic control and decreased postsurgical wound infections in non-diabetic patients. objectives the purpose of this study was to determine the effects of a new conditioning supplement on perioperative metabolic stress and clinical outcomes in non-diabetic patients. patient...

Coagulation is a complex physiological balancing mechanism that maintains haemostasis when blood vessels are injured. A hypercoaguable state as seen in early sepsis, cancer or pregnancy can cause arterial and/or venous obstruction with disruption of blood-flow and end organ damage. Similarly a hypocoaguable state can cause catastrophic haemorrhage and lead to death. Up to 20% of all blood trans...

We have assessed the value of routine preoperative tests in asymptomatic patients and their influence on anaesthetic and surgical decisions. We studied 3131 ASA I and II patients from four general hospitals undergoing elective surgical procedures. A retrospective review of the medical records revealed that 853 (27%) patients had some abnormal test result, of which 465 (15%) were previously unkn...

Patients with von Willebrand disease (VWD) frequently bleed under a challenge. The aim of our study was to identify predictive markers of perioperative major haemorrhage in type 1 (VWF:RCo = 15-30 IU dl(-1)) and possible type 1 (VWF:RCo = 31-49 IU dl(-1)) VWD patients. We recorded perioperative bleeding complications previous to diagnosis and laboratory parameters in 311 patients with 498 surgi...

OBJECTIVE To develop a convenient screening method that can predict perioperative venous thromboembolism (VTE) and identify patients at risk of fatal perioperative pulmonary embolism (PE). METHODS Patients hospitalized for gynecological abdominal surgery (n = 183) underwent hematology tests and multidetector computed tomography (MDCT) to detect VTE. All statistical analyses were carried out u...